@article{ author = {Motesharee, E and Rahimi, E and Asadi, N and Jafari, M and rafatifard, M and Mehbodi, M}, title = {Effects of Flexibility Exercise and Supplement Vitamin B6 on Primary Dysmenorrhea in Female Non-Athletes}, abstract ={Background & aim: Primary dysmenorrhea or painful menses in women's medicine is one of the most common complaints that are associated with physical and psychological symptoms. The aim of this investigation was to study the effects of an eight week flexibility exercise and use of vitamin B6 on physical and psychological symptoms of primary dysmenorrhea in non-athlete females. Methods: In this clinical trial study, 60 non-athlete females, were randomly divided into 4 groups control, exercise, vitamins and exercise plus vitamin. They engaged in an 8-week exercise program that includes flexibility training, stretching the abdominal muscles, lower back, hamstrings and pelvis and hip stretches. Eight movements, each movement with 3 times repetition and each repetition lasting 10 seconds during 4 days per week was performed. The vitamins group used 2 tablets of 40 miligaram B6 vitamin daily during the 8 week program starting 2 weeks before menstruation to 3 days after menstruation. In the exercise with vitamin group, during the 8 weeks of flexibility traininig program females used from 2 weeks before menstruation to 3 days after menstruation 2 tablets of 40 miligaram B6 vitamin daily. The control group had no intervention. Before and after eight weeks, participants completed the menstrual disorders’ questionnaire. Data were analyzed. Results: Significant decreases in average of physical symptoms(exercise from 28/4 to 6/7,vitamin from 25 to 9/35,training with vitamin from 27/66 to 4/40) and psychological symptoms (exercise 25/86 to 5/93,vitamin 24/99 to 3/53,training whith vitamin 27/73 to 3/36) was observed. But physical and psychological symptoms in post-test of exercise group with vitamin had a significant decrease as compared wih other groups (p≤0/05). Conculusion: 8 weeks of flexibility and vitamin B6 usage may reduce the physical and psychological symptoms of dysmenorrhea. Keywords: Dysmenorrhea primory, Flexibility exercise, Vitamin B6, Non-athlete girls *Corresponding Auther: Motesharee E, Department of Physical Education, Science and Rsearch Branch, Islamic Azad University Fars,Shiraz, Iran Email:El.motesharee@gmail.com}, Keywords = {Dysmenorrhea primory, Flexibility exercise, Vitamin B6, Non-athlete girls}, volume = {18}, Number = {7}, pages = {509-519}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-179-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-179-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Bahrebar, KH and MohseniKouchesfahan, H and Delavize, H and Nabiuni, M and Nazari, Z and Havasi, P}, title = {Surface Markers Expression in the Mesenchymal Stem Cells Derived from Bone Marrow}, abstract ={Background and aim: Mesenchymal stem cells were separated from bone marrow by Friedenstein et al. for the first time. In addition to their cohesion, mesenchymal properties of the cells were proven by surface markers. The aim of this study was to isolate mesenchymal stem cells from mouse bone marrow cultures and some surface markers in the obtained cells were expressed. Methods: In this study, bone marrow cells in the femur and tibia bones were isolated from NMRI mice. Bone marrow mesenchymal stem cells were isolated to the bottom of culture dish based on cohesion properties. In addition to their cohesion, mesenchymal properties of the cells were proven by CD73, CD44, CD90, CD31, CD45 and CD29 markers, after the fourth passage using flow cytometry. Results: In the primary culture, a heterogenous population of flattened, spindle and multi-faceted cells were observed. Spindle-shaped cells increased in later passages, so that almost all of third passage cells were spindle-shaped. Flow cytometry analysis of surface markers revealed high level mesenchymal stem cells from the fourth passage markers CD44, CD73 and CD29, and, low level of CD31, CD45 and CD90 markers. Conclusion: It can be concluded that MSCs derived from bone marrow mouse have some positive and negative surface markers with high and low expression, respectively. The expression rate of these markers proves the mesenchymal properties of cells. Keyword: Bone Marrow, Mesenchymal Stem Cells, Surface Markers}, Keywords = {Bone Marrow, Mesenchymal Stem Cells, Surface Markers}, volume = {18}, Number = {7}, pages = {520-529}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-181-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-181-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Niyyati, M and Ebrahimi, M and Haghighi, A and Haydari, S}, title = {Isolation and genotyping of Acanthamoeba spp. from recreational soil of parks in Tehran, Iran}, abstract ={Background & aim: Acanthamoeba is a genus of free-living amoebae found in environmental sources. These amphizoic amoebae can lead to severe human disease such as encephalitis and keratitis. Acanthamoeba transmits to humans through contact with soil and dust from scratching the skin. The aim of the present study was to identify the genotypes of Acanthamoeba in parks of the city of Tehran using molecular and morphological - based methods. Methods: In this study, 52 samples of soil were collected from 17 parks in Tehran. Samples were then filtered and cultured on 1.5% non-nutrient agar. DNA extraction and PCR amplification was performed using genus specific primers. Sequencing analysis and BLAST search were done for genotype identification. Results: Out of 52 soil samples, 14 strain (26.9%) were positive for Acanthamoeba amoebae by microscopic observation. Out Of 14 positive isolates, 9 (17.3%) were positive for Acanthamoeba using genus specific primer pairs. Of 14 strains, 9 were sequenced successfully. Genotype identification was revealed that all strains were belonged to T4 type. T4 genotypes among strains are human pathogens. Conclusions: Identification of pathogenic Acanthamoeba belonging to T4 genotype in recreational parks could be of utmost importance. Results of this study show that soil contamination, particularly in parks where children play and assemble is a sanitary risk for them. Key words: Acanthamoeba, Genotypes, Soil, Park}, Keywords = {Acanthamoeba, Genotypes, Soil, Park}, volume = {18}, Number = {7}, pages = {530-538}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-185-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-185-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Nazari, N and Ahmadi, M and Mazani, M and Alavimajd, H and Refaei, M and Hedayati, M}, title = {The diagnostic value of the lactate concentration in the vaginal fluid for diagnosis of premature rupture of membranes}, abstract ={Abstract Background & aim: Accurate and timely diagnosis of premature rupture of fetal membranes has a major role in reducing infant and mother mortality and morbidity .The purpose of this study was to determine the diagnostic value of the lactate concentration in vaginal fluid of pregnant women with premature rupture of fetal membranes (PROM). Methods: In this diagnostic study, 90 pregnant women with single pregnancy at the gestational age of 20-41 weeks were enrolled and randomly divided into two equal groups of 45. The first group includes pregnant women with premature rupture of membranes and the second groups were included pregnant women with intact membranes. To confirm or reject premature rupture of membranes, speculum examination, Fern and Nitrazyn was used in both groups. Lactate concentration test of vaginal fluid was performed by enzymatic colorimetric assay via handheld device Lactate Pro. Data were analyzed using descriptive statistics with SPSS 17 software. Results: Lactate threshold concentration was determined at level of 4.6 mM/L. Lactate concentration in vaginal secretions for the diagnosis of premature rupture of membranes, a positive test with a sensitivity of 95.6%, specificity 97.8%, the accuracy of the 96.6%, positive predictive value of 97.7%, , PPV 95.6% and negative predictive value of 95.6% were obtained respectively. Conclusion: Test of Lactate concentration in vaginal fluid test is a valid, quick and easy with high sensitivity and specificity for the diagnosis of premature rupture of membranes the fetus of pregnant women.}, Keywords = {Key words: Premature rupture of membranes, vaginal fluids, lactate level}, volume = {18}, Number = {7}, pages = {539-549}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-186-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-186-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Rahdar, M and Jelodar, A and Mola, K}, title = {Evaluation of Prevalence of Parasitic Infection in Lupus Erythematosus Patients in Ahvaz City in 2011-2012}, abstract ={Background & aim: Systemic lupus erythematosus is an autoimmune disease prevalent in many countries. Due to the use of immunosuppressive drugs to treat this disease, such patients are more likely to be afflicted by opportunistic infections and intestinal parasitic diseases. Aim of the current study was to recognize the prevalence of parasitic infection of these patients in Ahvaz city, 2011-2012. Methods: The study randomly assigned 100 stool samples from patients with systemic lupus erythematosus admitted to medical centers and hospitals of Ahvaz Imam Khomeini and Golestan. Samples were then sent to Parasitology Laboratory of Ahvaz Medical Sciences University and Lupus erythematosus was confirmed by a rheumatologist physician the samples were tested by direct, sedimentation technique, trichrome andziehl-neelsen staining for microscopic observation. The patient's data were obtained by questioner form and descriptive statistical was used for data analyzing. Results: At least 18% of the patients were infected by a single digestive cell. The highest rate of infection applied to Entamoeba Cola by 8% and the lowest applied to Giardia and Cryptosporidium by 2%. Helminthes infections were not observed in this study. Conclusion: Low rate of parasitic infections in patients with systemic lupus erythematosus in this study could be due to rising health care and public health data compared to previous years. Keywords: Lupus Erythematosus, Parasite Infection, Prevalence}, Keywords = {Keywords: Lupus Erythematosus, Parasite Infection, Prevalence }, volume = {18}, Number = {7}, pages = {550-558}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-187-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-187-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Momeninezhad, M and Karimi, AA and Mousavizadeh, A and Ostavar, and Delgoshaei, B and Ghaffarianshirazi, H}, title = {Authority Delegation in Boyerahmad Health Centers through Model to Combine Suggestions System and Delphi Method 2012}, abstract ={Background & aim: Authority delegation means to transmit part of organization`s manager and leader`s special authorities and executive duties, regardless its root to subordinates and heads of units and related offices to speed up implementing affairs and organizational purposes quickly and on time. The purpose of this study was to inspect authority delegation in health centers of Boyerahmad district through using model to combine suggestions (to identify process) and Delphi method (expert`s opinions) . Methods: This cross-sectional study was implemented in two stages at first stage, research community was authorities of Boyerahmad health centers (58 persons), their suggestions about requested processes to delegate were gathered by total count through open questionnaires and in second stage, which was Delphi, suggestions gathered from previous stage judged by 30 experts. Data of both stages analyzed by help of Chi-square, correlation coefficient tests. Results: Findings showed that 73.85% of suggestions were able to be delegated, based on expert`s opinion. 40% of suggestions were in domain of official, 36.92% financial and 23.08% hygienic. 88% less than 6 years management background. 20.69% had no academic studies and only 27% were general physicians. Conclusion: By participation of environmental management levels, several processes may be specified and identify cases which are possible to delegate them executively using Delphi (expert`s opinion) and this model can be used as a trust worthy method to delegate authority for decentralization. Key words: Participation Management, Health centers, Authority delegation}, Keywords = {Key words: Participation Management, Health centers, Authority delegation}, volume = {18}, Number = {7}, pages = {559-567}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-188-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-188-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Muosavi, E and Kalantari, M and Esmaieli, M}, title = {Investigating the effect of psychological debriefing and behavioral interventions on Post Traumatic Stress Disorder (PTSD) symptoms on veterans of Yasuj city}, abstract ={Background & aim: Considering that veterans as the most important target groups for health care facilities, and social psychology is taken into account, the aim of this study was to evaluate the efficacy of psychological debriefing and group behavioral interventions in reduction of posttraumatic stress disorder on veterans of Yasuj city. Methods: In this clinical-trial study, 20 patients were selected among veterans with post-traumatic stress disorder, and then randomly assigned to experimental and control groups. The Mississippi Scale for Posttraumatic Stress Disorder (M-PTSD) was administered by Research Tool to both groups before training. One session for psychological debriefing and 6-week sessions for behavioral interventions at 90-minute was conducted only for the experimental group. After a period of three months, the two groups were assessed to determine the effect of training. Data were analyzed using multivariate analysis of covariance. Results: The mean and standard deviation of posttraumatic stress disorder in patients after the intervention and control groups were 103/6±11/27 and 112±8/68, respectively. There was no significant difference between them (p<0.05). Conclusions: Treatment method of psychological and behavioral interventions can be effective in the treatment of chronic post-traumatic stress disorder. This therapeutic effect to be maintained even after three months. Key words: Post Traumatic Stress Disorder, Psychological Debriefing, Behavioral interventions}, Keywords = {Key words: Post Traumatic Stress Disorder, Psychological Debriefing, Behavioral interventions}, volume = {18}, Number = {7}, pages = {568-577}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-189-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-189-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Khatamsaz, S and Heidari, P and Shariati, M}, title = {The Study of Effects of Abscisic Acid (ABA) on Measure Serum Sex Hormones and Testis Tissue in Adult Male Rats}, abstract ={Background & aim: Nowadays the effects of plant-based foods in maintaining and improving the health of many diseases have been considered. The aim of this study was to investigate the effect of Abscisic acid on serum sex hormone levels and testis of adult male rats, respectively. Methods: In this experimental study, 50 male Wistar rats were randomly divided into 5 groups: control, sham and experimental groups 1, 2 and 3 respectively. The control group received no drug treatment. The sham group received distilled water as a solvent. Groups 1, 2 and 3 were administered orally with 20, 400 and 800 mg /kg of extract containing plant hormone Abscisic acid for 40 days respectively. At the end of the fortieth day from all groups blood samples were taken and serum hormones LH, FSH, dihydrotestosterone, and testosterone were measured by ELISA. Testicular tissue changes were studied by optical microscopy after preparation of tissue samples and lineage sperm counts between experimental and control groups were studied. The data were analyzed by ANOVA and t-test. Results : Abscisic acid extract with doses of 400 and 800 mg/ kg at the end of the fortieth day significantly increased serum testosterone levels than the control group (p<0.05). No significant differences in serum hormones LH, FSH and DHT were observed in the experimental group compared to the control group (p<0.05). Primary spermatocytes, borderline Sertoli between experimental and control groups were not seen (p<0.05). Histology of seminiferous tubules and spermatogenesis cell also had not changed. Conclusion : Possibly during a period of 40-day the effects of Abscisic acid on receptor function , through the impact on N- methyl-D-aspartate receptors and γ receptor by proxysom ( PPARγ) and activation of LH receptors in Leydig cells lead to testes activation and cause increase in secretion of testosterone. Key words: Abscisic acid, testosterone, dihydrotestosterone, LH, FSH, pituitary-gonadal axis}, Keywords = {Key words: Abscisic acid, testosterone, dihydrotestosterone, LH, FSH, pituitary-gonadal axis}, volume = {18}, Number = {7}, pages = {578-589}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-190-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-190-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Gousheh, MR and Pipelzadeh, MR and Akhondzadeh, MR and Olapour, AR and Alizadeh, Z and Sahafi, SA}, title = {Intraoperative Administration of Magnesium Sulfate on Post-Operative Pain of Inguinal Herniorrhaphy under General Anesthesia}, abstract ={Abstract Background & aim: Magnesium injection delays postoperative pain and hospital discharge. The aim of this study was to evaluate the effect of magnesium-sulfate infusion on postoperative pain in patients undergoing inguinal hernia surgery under general anesthesia. Methods: In the present clinical-trial study, 30 patients undergoing surgery Hernia Unilateral were randomly divided into two equal groups of treatment (infusion of magnesium sulfate 40 mg/kg and then 15 mg /kg/ hr during surgery and for 20 minutes afterwards and control (infusion of isotonic normal saline at the same condition). After surgery, postoperative pain was assessed using visual analogue scale (VAS) at 30 min, 2 h, 6, 12 and 24 after cessation of the infusion. The amount of analgesic consumption, vital signs and adverse events were investigated. Data were analyzed by chi-square and ANOVA. Results: VAS scores at 30 minutes, 2 hours, 6, 12 and 24 hrs postoperative and meperidine consumption in the magnesium sulfate group were significantly lower than the control group (P<0.05). Conclusion: Magnesium sulfate can successfully reduce the postoperative pain and narcotic consumption after surgery without any side effects after surgery. Key words: Inguinal Hernia - Pain, Postoperative - Magnesium Sulphate}, Keywords = {Key words: Inguinal Hernia - Pain, Postoperative - Magnesium Sulphate }, volume = {18}, Number = {6}, pages = {420-429}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-221-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-221-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Mazloum, V and Khayabash, KH and Rahnama, N}, title = {Comparing the Effects of Therapeutic Exercise and Hydrotherapy on Pain Severity and Knee Range of Motion in Patients with Hemophilia: A Randomized Controlled Trial}, abstract ={Abstract Background & aim: Pain and limited range of motion (ROM) are the crucial subsequent results of joint hemorrhages in patients suffering from hemophilia. Different training protocols designed to treat these patients are of great importance. The purpose of this study was to compare the effects of drought and water therapy on pain and range of motion of the knee in hemophilia patients. Methods: In this present clinical-trial study, 40 patients with hemophilia type A were randomly divided into three groups: exercise therapy on land, hydrotherapy, and control groups. The first two groups attended their special exercises on three days within 4 weeks, but the control group were only subjected to their daily life activities. Experimental pain, flexion and knee extension were measured using a visual analogue scale (VAS) and standard Goniometer at the beginning and after the intervention. Data were analyzed by ANOVA and Scheffe’s test (P<0.05). . Results: Both experimental groups exhibited significant reduction of pain along with improved knee flexion and extension compared with the control group (P<0.001). Pain reduction in subjects treated in water treatment was significantly higher than exercise group in drought (P0.05). Conclusion: The use of therapeutic exercise in water with regular exercise rehabilitation for patients with hemophilia can be helpful to reduce pain and improve range of motion in hemophilia patients. The effect of exercise therapy on pain reduction is more effective compared to traditional pain therapy. Key words: Hydrotherapy, Exercise Therapy, Hemophilia, Knee Range of Motion}, Keywords = {Key words: Hydrotherapy, Exercise Therapy, Hemophilia, Knee Range of Motion }, volume = {18}, Number = {6}, pages = {430-441}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-223-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-223-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Hosseini, E and Monsefi, M}, title = {Effects Of Anethum graveolens L. Etheric Fraction Of Ethanol And Aqueous Seeds Extracts On Sex Hormones And Histomorphometrical Changes Of Female Rat Reproductive System}, abstract ={Abstract Background & aim: Previous research confirmed the effects of ethanol and aqueous seed extracts on female reproductive system. The aim of this study was to evaluate the effect of alcohol extract of ether and aqueous fractions of dill seed histomorphometric changes in sex hormones and the reproductive system of female rats. Materials & Methods: The present experimental study was conducted on 35 female rats that were in estrus phase. Rats were divided into 5 groups, the control, low dose and high-ether fraction of aqueous extract 0.5 and 5 g/kg and fractions with high and low doses of alcohol0 .045 and 0.45 g/ kg respectively. The experimental group received 1 ml of mentioned dose and the control group received 1 ml distilled water daily for a period of 10 days. At the end of the experiment, the rats in the estrus phase were anesthetized and blood samples were taken from the dorsal aorta for more investigations. Ovaries and uterus tissue sections were prepared and stained with hematoxylin - eosin and Masson tri-chrome for morphometry by light microscopy. Levels of progesterone and estradiol levels were measured by radioimmunoassay and ELISA. Data were analyzed by one-way ANOVA. Results: Serum levels of progesterone and estradiol groups showed no significant difference between the experimental and the control group (P>0.05). In addition, the endometrial and myometrial thickness of uterus statistically decreased in high dose of etheric fraction of the aqueous extract (P<0.05). Conclusion: Oral administration of ether fraction of aqueous and alcoholic extracts of plant seeds will not be able to hormonal changes, as well as the other hormone-related variables. Key words: Dill seed, Estrogen, Progesterone, Etheric fraction, Reproductive system}, Keywords = {Key words: Dill seed, Estrogen, Progesterone, Etheric fraction, Reproductive system}, volume = {18}, Number = {6}, pages = {442-452}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-225-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-225-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Divsalar, A and Behroozi, J and Saboury, AA and Poursasan, NN}, title = {Preservative effects of Aspirin on Human Hemoglobin glycation in Diabetic Condition}, abstract ={Abstract Background & aim: Diabetes is a common disease which is characterized by hyperglycemia and the increase of protein glycation. The aim of this study was to investigate the effect of aspirin-induced damage in human hemoglobin in diabetic glycation. Materials & Methods: In this study, hemoglobin extracted from the blood of healthy individuals was incubated in the presence and absence of glucose and aspirin for 5 weeks. The rate of haem glycotation was determined in different conditions by studding products of Heam degradation, sort-band shifting and febrile state. Data were analyzed using One-Way analysis of Variance and Tukey’s test. Results: In the presence of aspirin, the amount of glycation reduced 50%. Furthermore, studies using band-shift sorting and febrile status indicated significant reduce in the amount of protein glycation in the presence of Aspirin. Conclusions: Aspirin reduces extent of glycation when hemoglobin is incubated in the presence of glucose. Likely, aspirin exerts its effect by acetylating amine groups in proteins. Key words: Diabetes, Glycation, Hemoglobin, Aspirin}, Keywords = {Key words: Diabetes, Glycation, Hemoglobin, Aspirin}, volume = {18}, Number = {6}, pages = {453-462}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-227-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-227-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Rafati, AR and Hashemi, SS and Hashemi, O}, title = {Effects of Cinnamon Extract on Cerebellum Histomorphometry in Diabetic Rats’ Fetus}, abstract ={Abstract Background & aim: In pregnant women, maternal diabetes occurs when the pancreas does not produce enough insulin, so glucose increases in the mother's blood and the blood of the fetus therefore causing many complications in children. The aim of this study was to evaluate the effects of cinnamon on morphometric histologic changes on fetal cerebellum of diabetic rats at days 18 and 20. Methods: In this study, 32 healthy female Wistar rats were prepared and randomly divided into four groups, normal control, diabetic, healthy subjects treated with cinnamon and cinnamon extract-treated diabetic groups. Diabetic groups were subjected by intraperitoneal of streptozotocin. All groups were charged with natural mating and they received a dose of 60 mg/ kg of cinnamon at the first day off pregnancy. After formation of the nervous system, in the eighteenth and twentieth day of pregnancy, the mother of the four mice were anesthetized and the fetus was removed for sampling. The histological slides were prepared and various parameters were studied in the cerebellum. Data were analyzed using one-way ANOVA and Duncan test. Results: The thickness of gray matter, and the gray matter white cells in the cerebellum of diabetic rats compared to other groups tested at days of18 and 20 and embryonic cells in the white matter of the cerebellum at day 18 was significantly decreased (p< 0.05). Conclusion: Administration of cinnamon extract reduces mothers’ blood sugar levels therefore preventing the complications of diabetes on the fetal cerebellum. Key words: cinnamon extract, Diabetes, cerebellum, Rat.}, Keywords = {Key words: cinnamon extract, Diabetes, cerebellum, Rat.}, volume = {18}, Number = {6}, pages = {463-474}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-228-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-228-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Siahpour, T and Nikbakht, M and Rahimi, E and Rabiee, MA}, title = {The Effect of 8 weeks aerobic exercise and yoga on primary dismenorrhea}, abstract ={Abstract Background & aim: Dysmenorrhea, menstrual cramps without physical pain is a common complaint in gynecology. The aim of this study was to investigate the effect of aerobic training on primary Dysmenorrhea in a period of 8 weeks. Materials & Methods: In the present clinical-trial study, 60 non-athlete girls with primary Dysmenorrhea were randomly divided into three groups: aerobic training, yoga and control groups. Based on the visual analog scale of pain intensity, pain duration and amount of analgesics administered was assessed before and after the period of primary Dysmenorrhea using a questionnaire. In this eight-week exercise program, the aerobic exercises group for 60 minutes in three weeks and yoga exercises group in three sessions per week for 60 minutes, the yoga breathing techniques, exercises, asana and relaxation techniques were performed. There was no intervention in the control group. Data were analyzed by Wilcoxon, Kruskal-Wallis and Mann Whitney (p0.05). There was a significant decrease in the analgesic consumption in the yoga group compared to the exercise group (p<0/05). Conclusion: Both aerobic and yoga are effective in the treatment of primary Dysmenorrhea, but yoga has a greater reduction property on drug dosage. Key words: primary dysmenorrhea, aerobic exercise, yoga exercise, female student}, Keywords = {Key words: primary dysmenorrhea, aerobic exercise, yoga exercise, female student }, volume = {18}, Number = {6}, pages = {475-483}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-230-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-230-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Karimzadeh, K and Hosseini, E and Kavoosi, E and Nasihatkon, A and Nikseresht, M}, title = {Hypolipidemic effects of hydroalcoholic extract from walnut male flowers on diabetic rats}, abstract ={Abstract Background & aim: Diabetes is a metabolic disorder resulting from defects in insulin secretion and function. In the current study we checked the Hypolipidemic effects of the walnut male flowers on the diabetic rats. Methods: 72 adult male Wistar rats (220-250g) were randomly selected and divided into three groups control group (n=8) without any intervention, induced diabetic group (n=32), 8 receiving normal saline and 24 receiving 3 different doses of extract (2, 4 and 6 g/kg), induced diabetic group (n=32) without treatment with extract. Diabetes was induced in rats by intraperitoneal injection of 60 mg/kg of streptozotocin. In the experimental groups, rats were treated for 15 days with a single dose of the extract for each day. At the first and end of the 15th day, a blood sample was taken from the experimental and control groups and the serum levels of glucose, TG, Cholesterol, and HDL-cholesterol were measured. Results: Our results showed that the hydro-alcoholic extract of walnut male flowers will decrease the levels of glucose , TG, Cholesterol, and LDL-cholesterol and increase the levels of HDL and HDL/LDL ratio in treated diabetic groups (P<0.05). The hypolipidemic effects of the extract were not dose dependent. Conclusion: Our results revealed the effectiveness of the hydro-alcoholic extract of walnut male flowers in diabetic rats by decreasing the blood glucose, TG, Cholesterol, and LDL-cholesterol and increasing the levels of HDL and HDL/LDL ratio. Based on these results, extract from walnut male flowers might have therapeutic effects on hypolipidemic of diabetes and more experiments, especially in human are necessary to confirm these results. Key words: diabetes, male flowers of walnuts, rat, streptozotocin, lipid}, Keywords = {Key words: diabetes, male flowers of walnuts, rat, streptozotocin, lipid }, volume = {18}, Number = {6}, pages = {484-694}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-232-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-232-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Shams, M and Shamsi, M}, title = {Increasing the Usage of Personal Protective Equipments in Constructing Subway Stations: An Application of Social Marketing Model}, abstract ={Abstract Background & aim: Although the relationship between the use of personal protective equipment and the reduction of workplace injuries is well-known the use of these devices during operation by the staff is not so desirable. This study was based on a model of social marketing interventions to increase the use of safety devices and personal protection on the subway-station staff. Methods: The present quasi-experimental study was based on the results of a formative research consisted of a qualitative (exploring employees’ views through focus group discussions) and a quantitative study (measuring attitudes and behaviors by questionnaire and checklist). Based on the formative research findings, a free package includes a helmet with a label containing the message, an anti-cut safety gloves, a dust mask, and an educational pamphlet were delivered to intervention group. After four weeks, the check list of observational behaviors in two constructing stations was completed and the results were compared with before intervention. The data were analyzed by paired t-test, t-test and logistic regression. Results: Three common behaviors were observed among staff not using caps, masks and gloves. The odds ratio for helmet and mask usage in the intervention group was more than other groups. After the intervention, the use of safety helmets and masks significantly increased (p < 0.05). The odds ratio for the use of helmets and masks after intervention in the intervention group was significantly higher than other groups (p < 0.05). Conclusion: The experimental basis of the safety devices and personal protection needs and demands of the audience, material and immaterial costs of the equipment, supplies, and promoting their use in the right place, can encourage the staff to continuously use the safety devices at workplace. Key Words: Workplace, Injuries, Personal Protective Equipment, Social Marketing}, Keywords = {Key Words: Workplace, Injuries, Personal Protective Equipment, Social Marketing }, volume = {18}, Number = {6}, pages = {495-508}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-234-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-234-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Taghavi, mm and Fatehi, F and Hassanshahi, G and Hoseini, SE and Hasani, J and Jamali, Z}, title = {The effective impacts of Angi- Pars on Expression of Some CXC Chemokines Group in STZ-Induced Diabetic Rats}, abstract ={Abstract Background & aim: Diabetes mellitus (DM) has destructive tissue effects via inducing oxidative stress. The aim of this study was to evaluate the Angi Pars effects on the expression of some CXC group of streptozotocin-induced diabetic rats. Methods: This experimental study was conducted on 48 male rats. Induced diabetic rats were done by 50 mg/ kg of Streptozotocin. 56 days after induction of diabetes, rats were randomly divided into 4 groups including control, untreated diabetic, insulin-treated diabetic and diabetic treated with insulin and Angipars. 24 h after the last injection the animals were bled and the expression of cxc Chemokines groups were measured by western blotting. Data were analyzed by t test. Results: Showed that CXCL10 was reduced in the treatment group and the treatment group receiving insulin in combination with angi - pars decreased significantly (P<0.05). The total concentration of CXCL12 chemokine showed that the concentration of the different groups did not change compared to the control group (P<0.05). The study showed that CXCL1 levels in the group receiving insulin in combination with angi-pars the chemokine concentration was significantly lower than the control group (P<0.05). Conclusion: Since, Angi-Pars consists of two major phenolic compound groups, 7 - hydroxy coumarin and flavonoids, has antioxidant, and controls the inflammatory effects of chemokine increase and balances between chemokines its effectiveness in angiogenesis can be maintain. Key words: Diabetes, Angi- Pars, Chemokines}, Keywords = {Key words: Diabetes, Angi- Pars, Chemokines}, volume = {18}, Number = {5}, pages = {337-346}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-319-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-319-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Mehrabi, s and Rahimi, f and GhafarinShirazi, HR and Hadinia,}, title = {Comparsion Efficasy of Ear Pyelogram versus Dye Contract Pyelogram in PCNL}, abstract ={Abstract Background & aim: Access to the collecting system is the first step in percutaneous interventions such as cutaneous nephrolithotomy (PCNL) and endopyelotomy.Usually "using air or contrast medium injected into the pelvis and Colle 'system which is obtained under fluoroscopic guidance. The purpose of this study was to compare the efficacy and adverse effects of air Pylogram with contrast in the PCNL procedure. Methods: In this clinical trial, 100 patients older than 18 years old with renal or upper ureteral stones and upper ureter since undergoing PCNL were randomly divided into two groups. In all patients undergoing spinal anesthesia, ureteral catheter F5 was placed in supine position and the patient was returned to the prone position. The control group was injected with15-40 ml of contrast material through the catheter to represent the pelvis and Colle under fluoroscopic guidance, the intervention group were injected with 40-15 ml of room air in a similar way. Then the standard PCNL procedures were performed in all patients. Demographic characteristics and intraoperative and postoperative variables such as access time to system, radiation, hypoxia, and cardiovascular and pulmonary complications in the two groups were compared. The data included descriptive statistics, frequency, mean, standard deviation were analyzed by Student's t-test. Results: The results showed the the age, sex and mean stone size were similar in both groups. Access time control systems in control group was 7/96±1/62 minutes and in the intervention group was 7/34±1/44 minutes (P=0/049) respectivly. In control group the radiation time was 1/06±0/30 min, and in the intervention group was 0/95±0/24 min (P=0/048). Hypoxia, pulmonary and cardiovascular complications has no seen in two groups. Conclusions: ]n order to represent of the pelvis and Colle in 'PCNL, the use of room air is feasible, safe and effective, time and duration of radiation have less access to the system and does not charge and can be a good alternative for Pylogram. Key words: Air pyelogram, Dye pyelogram, PCNL}, Keywords = {Key words: Air pyelogram, Dye pyelogram, PCNL}, volume = {18}, Number = {5}, pages = {347-355}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-320-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-320-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Maredpour, A and Naderi, F and Mehrabizadeh-Honarmand, M}, title = {Comparing the Efficacy of Eye Movement Desensitization and Reprocessing Therapy with Prolonged Exposure Therapy on the Trauma impact symptoms in Veterans Suffering from Chronic PTSD}, abstract ={Abstract Background and aim: Post-traumatic stress disorder is considered as set of symptoms developed afterward an individual witness, hear or involved. The current research was purposed to compare the efficacy of eye movement desensitization and reprocessing therapy with prolonged exposure therapy on the trauma impact symptoms in veterans suffering from chronic PTSD. Methods: in this clinical trail research randomly sampled 48 veterans diagnosed with PTSD who had psychiatric records in Salman City Hospital of Yasuj. The subjects devoted in three equal groups: two experimental and one control groups. As intervention procedures the two experimental groups were exposed to eye movement desensitization and reprocessing therapy (5 sessions) and prolonged exposure therapy (10 sessions) respectively. The control group received none. Subsequent to the treatment period the triple groups were post-tested by the prior pre test scales. The data were analyzed by implementing univariate analysis of covariance (ANCOVA) and Bonferroni post hoc test. Results: Both treatment procedures significantly reduced the trauma impact symptoms (p ≤0/001).The results also indicated that prolonged exposure therapy was more effective concerning the trauma impact symptoms improvement. Conclusion: Intervention treatment procedures such as eye movement desensitization, reprocessing therapy, and prolonged exposure therapy sustain sufficient efficacy in trauma impact symptoms improvement while prolonged exposure therapy exceeded significantly. Key words: Post Traumatic Stress Disorder, Eye Movement, Desensitization, Reprocessing, Prolonged Exposure Therapy}, Keywords = {Key words: Post Traumatic Stress Disorder, Eye Movement, Desensitization, Reprocessing, Prolonged Exposure Therapy}, volume = {18}, Number = {5}, pages = {356-367}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-322-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-322-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Kazemian, Z and Zadehbaghri, gh and Behmani, N and khalili, SH and Zadehbaghri, L and Abalfath, M}, title = {The efficacy of Self-regulation couple therapy on marital intimacy among infertile women}, abstract ={Abstract Background & aim: Considering the fact that infertility causes infertility problems in the marital relationship so, this study was aimed to determine the effectiveness of short-term couples therapy self-regulation on marital intimacy of infertile. Methods: In this clinical trial study, 20 couples were selected for sampling then they randomly into two experimental and control groups and each group was assigned 10 couples. Marital Intimacy scale was used to collect the data. Experimental intervention (self-regulatory couple therapy) was conducted on the experimental group for 8 sessions in duration of 90 minute per week. One month after completion of the training program, both groups were post-tested. Repeated measure was used to analyze the data. Results: The results showed that infertile couples marital intimacy increased self treatment groups compared with the control group (p<0.001). Conclusion: Short-term couple's therapy self-regulation is effective for increasing marital intimacy. Key words: Self-regulation, Couple Therapy, Marital Intimacy, Infertility}, Keywords = {Key words: Self-regulation, Couple Therapy, Marital Intimacy, Infertility }, volume = {18}, Number = {5}, pages = {368-379}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-324-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-324-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Kord, E and Shoushtari, A and Ghadakchi, H and Mohammadi, R and ,Hadinia, A}, title = {Phylogenetic analysis of Neuraminidase gene of avian influenza H5N1 subtype detected in Iran in 1390(2011)}, abstract ={Abstract Background & aim: Among the various subtypes of avian influenza viruses, an H5N1 subtype virus with high pathogenicity is of great importance. The aim of this study was to determine the Phylogenetic analysis of neuraminidase gene of avian influenza virus subtype of the H5N1 in Iran in 1390. Methods: In this experimental study, two swab samples from chickens with suspected symptoms of avian influenza were tested by the World Health Organization recommendation. The neuraminidase gene of positive samples was amplified by RT-PCR technique. After sequencing the phylogenetic studies were analyzed using MEGA5 and Megalign. Results: Phylogenetic analysis showed that the virus belongs to the Clade 2.3.2.1 which is highly similar to the viruses that are identified in Mongolia in 2010. Also in the stem of this virus neuraminidase protein a number of 20 amino acid has been deleted at position 69-49. Conclusion: Due to findings of this study, it seems that the virus has entered by migratory wild birds with the origin of Mongolia. Key words: Influenza, Avian, Neuraminidase}, Keywords = {Key words: Influenza, Avian, Neuraminidase }, volume = {18}, Number = {5}, pages = {380-388}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-327-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-327-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Ghavamizadeh, M and Mohammadi, J and Mirzaei, A and Sadeghi, H and Akbartabar, M}, title = {Cytotoxicity of Dorema auchri, Achillea millefolium and Artemisia aucheri by Artemia}, abstract ={Abstract Background & aim: Nowadays, toxic compounds derived from plants used against microbes and cancer cells. The aim of this study was to evaluate cytotoxicity of Dorema aucheri, Achillea millefollium and Artemisia aucheri using brine shrimp, Artemia urmiana, lethality test. Methods: In this experimental study, the plants were collected from the Kohgiluyeh and Boyer-Ahmad Province, then identified by a botanist. Clean and air-dried aerial parts of plants were extracted with suitable solvents. Cytotoxicity evaluation was performed using larvae hatched cysts were purchased from Urmia. Live larvae were exposed to different concentrations of extract and the numbers of live and dead larvae were counted after 24 hours. Mean of LC 50 of any extracts from control and exposed live larvae were examined. The data were analyzed using the Finney’s Probit analysis. Results: Hydro ethanol and chloroform extracts of Achillea millefolium, Dorema aucheri and Artemisia aucheri exhibited potent brine shrimp lethality with LC50 67.8±0.53μg.ml-1, 76.50±0.60μg.ml-1, 92.70±6.05μg.ml-1 respectively. The degree of lethality was found to be directly proportional to the concentration of extracts. Conclusion: According to BSLT, LC50 of D. aucheri, A. millefolium and A. aucheri, they were considered as toxic. So these plants could be a source of new compounds with biological activity. Key words: Artemia urmiana, Dorema auchri, Achillea millefolium, Artemisia aucheri, Cytotoxicity}, Keywords = {Key words: Artemia urmiana, Dorema auchri, Achillea millefolium, Artemisia aucheri, Cytotoxicity}, volume = {18}, Number = {5}, pages = {389-399}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-330-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-330-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Molaie, S and Mohebali, M and Molaie, A and Akhoundi, B and Zare, Z and MoradiAsl, E and ModarresSadrani, N and Rakhshidan, Z and Faragi, F}, title = {Distribution of Blood Groups(ABO) between Symptomatic & Asymptomatic Human Leishmania Infantum Infection in Human}, abstract ={Abstract Background & aim: According to the hypothesis that leishmania parasites can be escaped from immune system covered by blood group antigens (ABO) to prevent its recognition by the immune system. The aim of this study was to show the associated blood groups with symptomatic or asymptomatic visceral leishmaniasis due to Leishmania infantum in human. Methods: In this cross-sectional study the population was divided into two groups. The first group included 54 patients with kala-azar (antibody against Leishmania titers ≥1:3200 by TDA with clinical specificity) and the second group consisted of 45 subjects infected with Leishmania infantum (Leishmania antibody titers of1: 800 and 1:1600 by DAT method and non-specific symptoms). The distribution of the 4 main blood groups ABO type, sex, age, presence or absence of symptoms, clinical signs, and response to Glucantim therapy and DAT results were evaluated. Data were analyzed by chi-square test. Results: Most of the patients in group 1 were blood group A (37%) and the lowest number of blood group were B (12.8%). In the second group, most of the ABO blood group A (42.2%) and lowest in the ABO blood group AB (8.9%).There was no significant association between blood groups and clinical symptoms (p>0.05). Conclusion: This study showed that there is no association between blood group and incidence of symptomatic and asymptomatic kala-azar. Key words: Leishmania Infantum, Kala-azar, Blood Group, Human}, Keywords = {Key words: Leishmania Infantum, Kala-azar, Blood Group, Human}, volume = {18}, Number = {5}, pages = {400-409}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-332-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-332-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Ostovar, R and Fararuie, M and Mohamed, F}, title = {Comparison of Classic vs. Role plays Teaching Methods on the Menstrual Hygiene Behavior of Secondary School Girls in Iran}, abstract ={Abstract Background & aim: Awareness about the different aspects of health during puberty plays an important role in the health of girls and finally on their health future pregnancy. The aim of the present study was to to compare the effect of role playing and classical training methods in the the improvement of puberty health among secondary school girls in Yasouj City, Iran. Methods: In this study, the educational need during puberty school girls in the interview was determined. The two schools girls were randomly selected (students any school-60). Next, a knowledge and attitude questionnaire and a behavior checklist related to the main puberty health problems were completed. Then one of the schools randomly was selected as educational interventions schools and other were studied as controls. After grouping the students into four groups of 15, intervention were conducted in four sessions including: role-play, question and answer, and lecture. In the control group, all number of school students received training on puberty health through a classical education (lectures). The results were subsequently compared. Data were analyzed by Student t-test paired t-test, and analysis of variance. Results: The results of this study showed that the level of knowledge, attitude and behavior related to health matters during puberty showed significant improvement in the girls before and after implementation of educational intervention through role play (p<0.05).Thus, the mean score in group role play before intervention was 2.35±1.53 and after was 3.96±1.27 , The mean performance score before intervention 6.04±2.34 and after was, 8.61±1.55, respectively, while in classical group differences were not statistically significant (p<0.05) Conclusion: In comparison with the classical method of health education, teaching through role play significantly improved the level of knowledge, attitude and practice related to puberty health among adolescent girls. Key Words: Education, Adolescent Girls, Menstrual Hygiene, Role play, Classical Method}, Keywords = {Key Words: Education, Adolescent Girls, Menstrual Hygiene, Role play, Classical Method }, volume = {18}, Number = {5}, pages = {410-419}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-333-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-333-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Behnoud, F and Farahani, F and Ahmadi, M and Goudarzi, M and Rouhan, D and Shariatpanah, E}, title = {Comparison Adenoidectomy and Adenotonsillectomy’ effect on Changes in Symptoms of Chronic Rhinosinusitis}, abstract ={Abstract Background & aim: Chronic rhinosinusitis is a common diagnosis in children which affects the lives of patients and their families. The purpose of this study was to compare the effectiveness of adenoidectomy with adenotonsillectomy surgery in symptom’s changes in chronic rhinosinusitis in children less than 14 years of age. Methods: In the present clinical trial, 60 patients less than 14 years of age with a diagnosis of chronic rhinosinusitis resistance to antibiotic were randomly divided into two identical groups. In one group, adenoidectomy, and on the other group, adenotonsillectomy was performed. Prior to surgery and one month after surgery, symptoms of rhinosinusitis were graded based on the visual analogue scale. After surgery the Waters X-ray was taken. Data were analyzed by independent t-test. Results: In both groups, VAS changes in symptoms, headache, cough, postnasal discharge, bad breath, rhinorrhea, and nasal obstruction were significant before and after surgery (p.>0.5 ). Also the mean change in VAS before and after surgery in adenotonsillectomy adenoidectomy was significant (p.>0.5). In this study, reduction of clinical signs and symptoms of rhinosinusitis after adenoidectomy surgery was 100%, but the improvement of Waters X-ray findings was 53%. Reduction of signs and symptoms of rhinosinusitis after adenotonsillectomy surgery was 100%, but recovery process of waters radiographic of rhinosinusitis findings was 80%. Conclusion: Adenotonsillectomy and adenoidectomy surgery were effective in improving of the process of sign and symptoms and radiologic findings in children with chronic rhinosinusitis moreover adenotonsillectomy surgery was more effective in improving symptoms and waters radiological findings. Key words: Adenoidectomy, Adenotonsillectomy, Rhinosinusitis}, Keywords = {Key words: Adenoidectomy, Adenotonsillectomy, Rhinosinusitis}, volume = {18}, Number = {4}, pages = {252-260}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-337-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-337-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Dadfar, F and Hoseini, E and Bahaoddini, A and Mokhtary, M and Razm, N}, title = {The Interaction of Hydroalcoholic Extract of Ginger Rhizome (Zingiber officinale) and Adrenergic System on the Mechanical Activity of Isolated Trachea of a Male Rat}, abstract ={Abstract Background and aims: Due to the increasing interest in studying the plant extracts in various fields of biology, the aim of the present study was to investigate the effect of ginger extract interaction and adrenergic system on the mechanical activity of the a rat’s isolated trachea. Methods: In this experimental study, 15 adult male rats were anesthetized after adaptation to environment. Afterwards, the trachea was removed and divided into 3 mm segments. The isolated tracheal rings of each mouse were divided into control and experimental groups. Next, they were put in tissue baths containing oxygenated Krebs solution, and their mechanical activity were recorded by the transducer and bridge amplifier system. In the experimental group, hydroalcoholic extract of ginger (0.5 mg/ ml) was added to the tissue bath. In the same conditions, the solvent extract was added to the control group. At the end, the mechanical response of each group in the presence of propranolol and isoprenaline as agonist and antagonist adrenergic system were recorded. The gathered data were analyzed by the paired t-test. Results: In the presence of hydroalcoholic extract of ginger, the mechanical activity of isolated trachea was significantly decreased compared to the controls (p < 0.05). However, after injection of isoprenaline and propranolol, a significant difference in the mechanical activity of the trachea was observed in the experimental group compared to the control group (p < 0.05). Conclusion: This study showed that the ginger has effects on isolated tracheal relaxation via other routes, except the adrenergic system. Keywords: Adrenergic system, Mechanical activity, Trachea, Ginger}, Keywords = {Keywords: Adrenergic system, Mechanical activity, Trachea, Ginger }, volume = {18}, Number = {4}, pages = {261-271}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-339-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-339-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Khaksar, Z and TavakolKookhdan, E}, title = {Effect of Fenugreek Seed Extract (Trigonella Foenum-graecum) on Brachial Region of the Spinal Cord of an 18-Day Old Rat Offspring with Diabetes}, abstract ={Abstract Background & aim: Diabetes can affect the spinal cord, an important part of the central nervous system. Fenugreek seed has been suggested to have potential antidiabetic effects. This study was conducted to assess the effects of Fenugreek seed extract (trigonella foenum-graecum ) on fetal spinal cord structure, specifically in the brachial enlargement cord in an 18-day old fetus of diabetic mothers treated with extracts in comparison with the control groups' mothers. Methods: In the present cross-sectional study, sixteen healthy female rats were randomly divided into four equal groups: Healthy control, Diabetes control, Fenugreek control, Fenugreek treatment. Diabetes was induced by intraperitoneal injection of Streptozotcin (50 mg/kg). All four groups became pregnant by natural mating. After formation of the nervous system, two fetuses from each group were expelled by cesarean after performing anesthesia on the animals on 18th day of pregnancy furthermore their brachial enlargement spinal cord samples were taken. Finally, the tissue sections were prepared by routine procedures and diverse histological parameters were examined. The collected data were analyzed by one-way ANOVA. Results: results showed that fetal body weight on the diabetic control group was significantly higher compared to the other groups (P≤ 0/05). Moreover, significant reductions in the transvers and vertical diameters in central channel of the spinal cord and as well in the number of neurons of the spinal cord gray matter in the diabetic control groups in comparison with the other groups were observed (P≤0/05). Conclusion: The hyperglycemic effect of maternal diabetes during fetal period causes abnormalities, especially in the brachial enlargement of spinal cord, including changes in the spinal cord and neurons number in the gray matter. Disorders occurring in the prenatal remains and may perhaps cause lack of ability to perform certain physical activities. Key words: Fenugreek, Streptozotocin, Diabetes, Spinal Cord}, Keywords = {Key words: Fenugreek, Streptozotocin, Diabetes, Spinal Cord}, volume = {18}, Number = {4}, pages = {272-283}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-340-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-340-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Hosseini, SA and Nikbakht, H and Azarbayjani, MA}, title = {The Effect of Aqua Extract of Saffron with Resistance Training on Glycemic Indexes of Streptozotocin Induced Diabetic Rats}, abstract ={Abstract Background & aim: According to the proven effectiveness of saffron resistance and physical activity on diabetes, the aim of this study was to evaluate the effect of glycemic indexes of saffron combined with resistance training on streptozotocin induced diabetic rats. Methods: The present experimental study was conducted on 36 adult male rats. After induction of diabetes, the rats were randomly divided into four equal groups, resistance exercise (five days a week, for six days) and saffron extract (25 mg/L daily), resistance exercise combined with saffron extract and control groups. After a period of six weeks, glycemic indexes were measured. The gathered data were analyzed by klomogrov – Smirnov, one-way ANOVA and Tukey tests. Results: The results showed that fasting glucose in saffron aqua extract combined with resistance training group was significantly lower than both control and the RT groups ( p=0,014). Glycosylated hemoglobin group of saffron combined with resistance training was lower than the control group (p=0.011). Insulin resistance combined with resistance training in saffron aqua extract was lower than the control group (p=0.011). Conclusion: Six weeks of resistance training and consumption of saffron alone had a significant effect on glycemic indexes. However, saffron supplements with resistance training had a greater effect on control of fasting blood glucose. Key words: resistance training, saffron, glucose, HbA1C, insulin resistance, diabetes}, Keywords = {Key words: resistance training, saffron, glucose, HbA1C, insulin resistance, diabetes}, volume = {18}, Number = {4}, pages = {284-294}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-341-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-341-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Hosseinzadeh, K and Choobineh, A and Ghaem, H}, title = {Validity and Reliability of the Farsi Version of the Individual Strength Questionnaire Checklist in the Iranian Working Population}, abstract ={Abstract Background & aim: Significant attention is paid towards Work-related fatigue for its adverse health effects. The Checklist for Individual Strength (CIS) is an instrument for measuring fatigue. The aim of this study was to determine the reliability and validity of the Persian version of an Iranian working population in the checklist individual strength. Methods: In this cross-sectional study, in order to determine the linguistic validity, the CIS was translated into Persian. The Farsi version was translated into English by another professional translator. Farsi to English translation of the original English version was sent to the author for comparison. After comparison and verification by the author, the final version of the P-CIS was prepared in a pilot study to assess the strength of understanding. In order to evaluate the reliability and validity of the P-CIS, 200 people working in a cosmetics factory along with office employees at Yasuj health centers were studied. To assess reliability and internal consistency of the questionnaire, Cronbach's alpha coefficient was used. Using the Spearman correlation coefficient, convergent validity was examined. Validity was assessed through factor analysis. Results: The Cronbach's alpha coefficient of reliability of the total questionnaire, mental fatigue, reducing activity, reducing of the concentration, and reduction of motivation were 0.86, 0.83, 0.72, 0.59, and 0.37 respectively. Spearman correlation coefficients were obtained for the validity range of 0.43-0.88. Based on the weight factor obtained in the aspect of mental fatigue and reduced activity of the P-CIS showed acceptable validity Conclusion: The P-CIS had satisfactory linguistic validity and psychometric properties for measuring fatigue in the Iranian working population. Key words: Fatigue, Checklist Individual Strength (CIS), Validity, Reliability}, Keywords = {Key words: Fatigue, Checklist Individual Strength (CIS), Validity, Reliability}, volume = {18}, Number = {4}, pages = {295-304}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-342-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-342-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Vazin, A and Hamedi, M}, title = {The Correlation between Defined Daily Doses of Antibiotics with the Antimicrobial Resistance of Microorganisms Separated from Patients with Nosocomial Infections}, abstract ={Abstract Background & aim: Infection with resistant microorganisms in intensive care units (ICUs) is more prevalent than other parts of the hospital. The aim of this study was to determine the relationship between the daily dose of the antibiotic resistance and patterns of microorganisms isolated from patients with nosocomial infections. Methods: This cross-sectional study was conducted in a period of 9 months in three wards of ICU, internal medicine, neurosurgery of Namazi Hospital of Shiraz. The World Health Organization definition was used for determining the daily Dose. The sensitivity test of microorganisms to antibiotics was determined by E-test. The collected data were analyzed with Pearson test. Results: The highest incidences of nosocomial infection were observed in intensive care medicine and surgery, respectively. The total amount of consumed antibiotics were seen in intensive care of surgery, internal medicine and neurosurgery were 100.29 DDD/100 bed days. Uses of cephalosporins, especially third generation cephalosporins show the highest amount. The resistance rate of gram-negative bacteria such as Acinetobacter, Pseudomonas and Enterobacter to ceftriaxone were100, 100 and 82.4% respectively. Conclusion: The results of study showed that there was a relationship between antibiotic consumption and resistance of microorganisms. Although other variables than the antibiotic consumption causing antibiotic resistance should not be ignored. Key words: Defined daily dose, Intensive care unit, Antibiotics, Antibiotic resistance, Nosocomial infection}, Keywords = {Key words: Defined daily dose, Intensive care unit, Antibiotics, Antibiotic resistance, Nosocomial infection}, volume = {18}, Number = {4}, pages = {305-314}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-343-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-343-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Vazin, A and Hamedi, M}, title = {The Correlation between Defined Daily Doses of Antibiotics with the Antimicrobial Resistance of Microorganisms Separated from Patients with Nosocomial Infections}, abstract ={Abstract Background & aim: Infection with resistant microorganisms in intensive care units (ICUs) is more prevalent than other parts of the hospital. The aim of this study was to determine the relationship between the daily dose of the antibiotic resistance and patterns of microorganisms isolated from patients with nosocomial infections. Methods: This cross-sectional study was conducted in a period of 9 months in three wards of ICU, internal medicine, neurosurgery of Namazi Hospital of Shiraz. The World Health Organization definition was used for determining the daily Dose. The sensitivity test of microorganisms to antibiotics was determined by E-test. The collected data were analyzed with Pearson test. Results: The highest incidences of nosocomial infection were observed in intensive care medicine and surgery, respectively. The total amount of consumed antibiotics were seen in intensive care of surgery, internal medicine and neurosurgery were 100.29 DDD/100 bed days. Uses of cephalosporins, especially third generation cephalosporins show the highest amount. The resistance rate of gram-negative bacteria such as Acinetobacter, Pseudomonas and Enterobacter to ceftriaxone were100, 100 and 82.4% respectively. Conclusion: The results of study showed that there was a relationship between antibiotic consumption and resistance of microorganisms. Although other variables than the antibiotic consumption causing antibiotic resistance should not be ignored. Key words: Defined daily dose, Intensive care unit, Antibiotics, Antibiotic resistance, Nosocomial infection}, Keywords = {Key words: Defined daily dose, Intensive care unit, Antibiotics, Antibiotic resistance, Nosocomial infection}, volume = {18}, Number = {4}, pages = {305-314}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-345-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-345-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Mehrabi, S and Rezaie, M and Shahbazipar, M and Zoladl, M and Jannesar, M}, title = {Effective factors of Pediatric Urolithiasis in Children under 14 years old that Refer to pediatric and urologic Medical Center of Yasuj at 2010}, abstract ={Abstract Background & aim: Urinary stone is one of the important causes of morbidity among children. The aim of this study was to determine the effective factors of Pediatric Urolithiasis in Children under the age of 14. Methods: In this case-control study, among children under 14 years of age referring to the Shahid Beheshti Clinic of Yasuj with the diagnosis of urolithiasis confirmed twice by ultrasound, 48 children were selected as eligible cases for the questionnaire containing demographic information, the location, and size of the stone were completed. Of 48 healthy children younger than 14 years referring to the clinic for evaluation of growth and health were selected as the control group. Affecting parameters of serum and urinary stone formation in both groups were controlled. The collected data were analyzed by using statistical mean tests, chi-square and t-tests. Results: In 70.8% of the group case, children had a positive family history of urolithiasis. Hypercalciuria, Hyperoxaluria, hyperuricosuria, and Hypocitraturia were found 35.4%, 17.8%, 13.6%, and 13.6% in group case respectively. Mean urinary calcium level of the case group was 0.47 and in controls, 0. 24. The mean urinary uric acid level of the case group was 0.91 and for the control was 0.54 (05/0> p). In 58.3% of the cases, a single kidney stone was seen and in 95.8% of the cases, the size of 4 mm or less were observed. The most common symptoms of urolithiasis (58.1%) at admission were restlessness and irritation during urination. Conclusion: According to the results of study, Hypercalciuria, Hyperoxaluria, Hyperuricosuria and positive family history are the major cases of urinary stones in children which are often individual with the size of 4 mm. Key words: urolithiasis, children, hypercalciuria}, Keywords = {Key words: urolithiasis, children, hypercalciuria}, volume = {18}, Number = {4}, pages = {315-326}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-346-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-346-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Maraghi, S and YadYad, MJ and Sheikhi, M and LatifiS, M}, title = {Frequency of Anti- Toxoplasma Antibodies in Midwifery and Nursing Students of Abadan Islamic AzadUniversity Students in 2011}, abstract ={Abstract Background & Aim: Toxoplasmosis is a common parasitic infection among humans and animals, with worldwide prevalence. The aim of this study was to determine the prevalence of anti-Toxoplasma antibodies in midwifery and nursing students. Methods: In the present cross-sectional study conducted in 2011, 240 students were randomly selected. Then, 5 ml of blood sample was collected from each student. After centrifugation, the blood serum were detected and tested for antibodies against Toxoplasma gondii by ELISA. The collected data was analyzed by chi-square test. Results: The frequency of anti- Toxoplasma (IgG ,IgM) antibodies in all students were 11.67% and 12.08% respectively. This frequency for midwifery students were 11.67% and 10.84, and in nursing students were 11.67% and 13.33% respectively. Seven cases (2.92%) were positive for both IgG and IgM and 2 cases were positive for IgG, and IgM was on the borderline. Between positive antibodies and factors such as drinking water, consumption of meat products, vegetables and cats holding no significant association was seen (p <0.05) Conclusion: The results of this study indicated that 78.92% of the students were sero- negative and at high risk of infection. Due to the age of these students, they should be instructed to prevent congenital toxoplasmosis during pregnancy. Key words: Toxoplasmosis, Frequency, ELISA, Girls}, Keywords = {Key words: Toxoplasmosis, Frequency, ELISA, Girls}, volume = {18}, Number = {4}, pages = {327-336}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-348-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-348-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Mohebalian, H and Dalirezh, N and Morshedi, A}, title = {The Effect of Histamine on Dendritic Cells Pulsed with Myelin Proteins and Autologous T Cell Response in Vitro}, abstract ={Abstract Background & aim: The role of dendritic cells in the immune responses has led to the application of these cells in autoimmune diseases such as multiple sclerosis. The aim of this study was to investigate the effect of histamine on dendritic cells pulsed with myelin proteins and autologous T cell response in vitro. Methods: In this experimental study, blood samples were taken from 5 volunteers. Subsequently, peripheral blood mononuclear cells were isolated by using Phicole Hypaque. Using GM-CSF cytokine and IL-4, dendritic cells were produced from peripheral blood and then stimulated with MBP in the presence and without histamine in control and treated group to be matured. The CD14+ and surface markers of resulted DC were evaluated by Flowcytometry. The levels of cytokines IL-10 and IL-12 in dendritic cells culture and IL-4, and IFN-γ in both cultured dendritic cells and antilogous T cells were obtained. And then the proliferation of T lymphocytes in the treatment and control groups were compared. The collected data was analyzed by Student's t-test and ANOVA. Results: In the treatment group, the expression of CD83 (from 3/15 to 5/24%) and HLA-DR (from 3/26 to 38%) was significantly higher than the control group (P> 0.05). The expression of CD14 exhibited no change. The secretion of IL-10 increased and IL-12 showed a decrease. The secretion of IL-4/IFN- ᵞ showed an increase in treated group than the control group (P ˂ 0/05). Conclusion: Histamine deviation with immune responses from TH1/TH17 to the TH2 in an experimental model of MS can be used as a new method of DC-based vaccines which may be useful in treating this disease. Key words: Denderitic Cells, Myelin Basic Protein (MBP), Histamine, Multiple sclerosis (MS)}, Keywords = {Key words: Denderitic Cells, Myelin Basic Protein (MBP), Histamine, Multiple sclerosis (MS)}, volume = {18}, Number = {3}, pages = {163-172}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-350-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-350-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Hatami, H and BananKhojasteh, SM and RajabzadeMozirajy, M}, title = {The effect of Crystal Meth on Anxiety Related Behavior in Male Rats}, abstract ={Abstract Background & aim: Consumption of methamphetamine compounds, especially with heavy usage, is associated with memory impairment and depression in the elevated spaces. The aim of this study was to alleviate the effect of crystal meth on Anxiety-related behaviors in male rat. Methods: In the present study, twenty-eight rats were randomly divided into four groups: treated with saline, with crystal meth dosages of 5, 10 and 15 mg/ kg respectively. Crystal meth injection duration was seven days. Factors associated with anxiety in the elevated plus maze model were evaluated at the first, fourth and seventh day. Data were analyzed by one-way ANOVA. Results: The injections of crystal meth in three days lead to the decrease of chronic and acute anxiety. Crystal Meth in two doses of 10 and 15 mg kg per day increased the percentage of time spent in the open arm (p <05). In days 4 and 7, the percentage of time spent in open arms and percentage of open arm and entry percentages of the group receiving crystal meth in comparison to saline group showed a significant increase p<0.05). Conclusion: The results suggested that crystal meth possess capability to activating neural mechanisms in the control of anxiety. In fact, crystal meth in a dose- dependent usage can increase the probability of high risk behavior in users by anxiety reduction. Key words: Anxiety, Crystal Meth, Elevated Maze}, Keywords = {Key words: Anxiety, Crystal Meth, Elevated Maze}, volume = {18}, Number = {3}, pages = {173-183}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-352-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-352-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Faramarzi, M and RahimiKashkouli, Y and RahimiKashkouli, HR and Gholamzadeh, D}, title = {Production of Dextran from Sugar Cane Molasses by Leuconostoc mesenteroides}, abstract ={Abstract Background & aim: Dextran is a polysaccharide consisting of glucose monomers that are widely used in medicine as a blood volume extender. The aim of this study was to produce dextran from cane molasses using Leuconostoc mesenteroides bacteria. Methods: In this experimental study, for bacterial growth and dextran production, sugarcane molasses was added to the culture medium at different concentrations. Dextran sedimentation was obtained by shaking and centrifugation by adding ethanol after 48 hours. Response surface design was used for qualitative identification of the polarization of dextran and statistical analysis methods. Results: After assessing the separation and interactive effects of the parameters on the optimum amount of dextran produced from sugarcane molasses as 50 g, 35 º C and 5/8 = pH , the Dextran produced was more than 82 g/l. The correlation of the computational model for the dextran produced was 99.5%, which indicated excellent agreement with the experimental and computational models of high accuracy. Conclusion: Dextran produced by Leuconostoc mesenteroides bacteria and sugarcane molasses as substrate, is a cheap and affordable compared to current methods of dextran production. In addition to producing a clinical product, the molasses pollution could be dramatically decreased. Key words: Dextran, Molasses, Leuconostoc Mesenteroides}, Keywords = {Key words: Dextran, Molasses, Leuconostoc Mesenteroides}, volume = {18}, Number = {3}, pages = {184-193}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-354-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-354-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Jafary, AA and Latifi, AM and Shohrati, M and HajiHosseini, R and Salesi, M}, title = {The Effect of Scrophularia striata Extracts on Wound Healing of Mice}, abstract ={Abstract Background & aim: Scrophularia striata extract has been traditionally used for wound healing. The aim of this study was to evaluate the effect of Scrophularia striata extract on wound healing on mice. Methods: In this experimental study, a number of 35 male mice (NMRI) weighing 25-30 g were divided into 5 equal groups. Two 6 mm circular wounds were punched on the back of the mice moreover they were treated for 3 weeks in separate cages. The first group wasconsidered as the control group and the other groups were treated with phenytoin ointment 1%, alcoholic extract, hydroalcoholic and aqueous 10% twice a day for 21 days respectively. The wounds were daily photographed by a digital camera and the wound area was calculated using Image J software. Data were analysed by Kruskal-Wallis and Mann-Whitney test. Results: The average healing duration in the control group, phenytoin and extracts, aqueous and alcoholic were 9.1 ± 3 6, 6.6± 1.9, 6.5 ± 1.7, 6.7 ± 1.8 and 6.1 ± 0.9 days respectively. The remaining scar size in these groups were 9.08 ± 1.83, 5.84 ± 1.20, 3.7 ± 0.62, 3.5 ± 0.74 and 2.81 ± 0.79 millimeters respectively. The average duration of scar healing and the remaining treatment groups were significantly different from controls (p<0.05). Conclusion: Scrophularia striata extract decreased the period of wound healing in mice. Among the three types of extracts, the hydroalcoholic extract demonstrated the best result. Key words: Scrophularia striata, Healing, Extract, Mice}, Keywords = {Key words: Scrophularia striata, Healing, Extract, Mice}, volume = {18}, Number = {3}, pages = {194-209}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-355-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-355-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Fanimakk, O and Afzali, N and Omidi, A and Shibak, A}, title = {Comparison of Aflatoxin B1 production by Aspergillus flavus and Aspergillus parasiticus under various conditions of temperature, light and pH}, abstract ={Abstract Background & aim: Aflatoxins are a large group of mycotoxins. The aim of the present study was the comparison of Aflatoxin B1 (AFB1) production by Aspergillus flavus (IR 111) and Aspergillus parasiticus (NRRL 2999) under various conditions of temperature, light, and pH. Methods: In this experimental study, twenty-four flasks were assigned for incubation of each of the fungi A. Flavus and parasiticus at 18, 24, 32 °C. Both flasks were maintained under conditions of light and darkness. The rate of (AFB1) produced by each groups, was measured by thin layer chromatography. Data were analyzed using descriptive statistical analysis (SPSS, version 16). Results: The lowest yield of (AFB1) produced by A. Flavus and parasiticus belonged to 32 °C and pH 6.5, respectively. On the other hand, the highest yield of toxin was observed at 24 °C and pH 6. The lighting effects were considerable. According to the studies on the adverse effects of light and the fermentation process, aflatoxin production increased in dark conditions. Conclusion: The results of study showed that A. Parasiticus (NRRL 2999) produced more aflatoxin than A. Flavus (IR 111). Key words: Aflatoxin B1, Aspergillus flavus, Aspergillus parasiticus}, Keywords = {Key words: Aflatoxin B1, Aspergillus flavus, Aspergillus parasiticus }, volume = {18}, Number = {3}, pages = {210-218}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-356-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-356-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Gerayesh-Borazjanian, H and Rasooli, A and Shahryari, A and Najafzadehvarzi, H and Nouri, M}, title = {Comparison of the Antioxidant Properties of Vitamins E, C and Copper in the Prevention of Molybdenum Toxicity in Rabbits}, abstract ={Abstract Background & aim: Oxidative stress is defined as an imbalance between oxidants and reluctant in the individual or its cells. The aim of this study was to compare the effects of antioxidant vitamins E and C in prevention of the toxicity of copper and molybdenum in rabbits. Methods: In this experimental study, 25 adult rabbits were randomly divided into 5 groups. The first group (control group) received no medication The second group received 80 mg/Kg/day sodium molybdate orally until symptoms of toxicity, the third group received 4 mg/kg of copper sulfate orally with sodium molybdate, Group IV 150 mg/kg of vitamin E with sodium molybdate orally, and group V 20 mg/kg orally received vitamin C with sodium molybdate. Using the total antioxidant capacity parameters, malondialdehyde and ceruloplasmin levels in rabbit’s serum parameters levels of oxidative stress and antioxidant defense were obtained after a 35-day trial. The obtained data was analyzed using ANOVA and Turkey's test. Results: The results of the present study indicated that molybdenum induced alopecia and depigmentation and molybdenum as a stress factor increased levels of malondialdehyde. So that the amount of malondialdehyde from 1.285 in the control group to 1.849 µM/L Molybdenum increased significantly. Although this indexes in the groups receiving vitamin E and C decreased significantly from 0.375 to 0.426 µM/L respectively. However, the total antioxidant capacity in any of the groups compared with the control group showed no change. Conclusion: Molybdenum toxicity is involved in the pathogenesis of oxidative stress and antioxidant agents of vitamins E and C can reduce its toxic effects. Key words: Antioxidant, Molybdenum, vitamin E, vitamin C, Copper, Rabbit}, Keywords = {Key words: Antioxidant, Molybdenum, vitamin E, vitamin C, Copper, Rabbit }, volume = {18}, Number = {3}, pages = {219-227}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-357-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-357-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {MohammadAlizadehchrnabi, S and Kamalifard, M and Ebrahimimamagani, M and Asgharijafarabadi, MA and Omidi, F}, title = {The Effect of Educational Package on Nutritional Knowledge and Behavior toward the Coping with Complication and Supplement Consumption}, abstract ={Abstract Background & aim: Proper nutrition is essential in the prevention and improvement of maternal problems and fetal health during pregnancy. The aim of this study was to determine the effect of nutrition education package on knowledge and nutritional behavior of pregnant women coping with problems and taking supplements during pregnancy. Methods: In the present clinical trial, a number of 88 pregnant women referred to health centers in Karaj, Iran, were selected and randomly divided into two groups (Intervention and control group). Two sessions of approximately 60 minutes including classes on nutrition during pregnancy was held for the intervention group using presentation, booklets, and educational film sex education with similar method was held for the control group. Data were collected through a questionnaire. The collected data was analyzed by analysis of variance with repeated measures analysis of covariance and logistic regression analyzes. Results: In the intervention group, in the field of knowledge dealing with problems during pregnancy and after the intervention supplements in two stages were significantly higher than the control group (p˂001). Scores in the intervention group in the field of nutritional problems during pregnancy included constipation, heartburn, swollen hands and feet, anemia and urinary tract infections during both stages of the intervention were better than the control group (p˂005). Iron and multivitamin supplementation in the intervention group during two phases after the intervention phase was better than the control group (p˂005). Conclusion: The content of educational package was evaluated as an appropriate policy in promoting nutritional knowledge and behavior among pregnant women. Key words: Education, knowledge behavior, nutritional supplements, pregnancy}, Keywords = {Key words: Education, knowledge behavior, nutritional supplements, pregnancy}, volume = {18}, Number = {3}, pages = {228-240}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-358-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-358-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Gordanian, B and Behbahani, M and Carapetian, J and Fazilati, M}, title = {Evaluation of Cytotoxicity of Sagebrush Plain Extract on Human Breast Cancer MCF7 Cells}, abstract ={Abstract Background & aim: Several studies have reported anti-cancer properties of sagebrush plain. The aim of this study was to evaluate the cytotoxicity of the methanol extract of sagebrush plain on human breast cancer MCF7 cells. Methods: In the present experimental study, the toxic effects of methanol extracts of flowers, leaves, stems and roots of sagebrush plain from of Khorassan and Esfahan province were tested on human breast cancer cells MCF-7 and normal cells HEK293 . Plant samples were extracted by methanol and their toxic effects on normal and breast cancer cells at concentrations of 5.62, 125, 250 and 500 µg/ml was determined by MTT. Both breast cancer cells MCF-7 and normal HEK293 cells were cultured in RPMI-1640 medium and DMEM containing 10% fetal calf serums were cultured. Data were analyzed by one-way ANOVA. Results: The methanol extract of sagebrush showed toxicity on MCF7 cells. The extract of Khorasan showed higher toxicity than Esfahan province. IC50 of sagebrush plant for all parts of the plant were obtained more than 500 µg/ml, but the IC50 of sagebrush plant of Khorasan region in leaf and flower were 205 ± 1.3 and 213 ± 5.3µg respectively. The leaves and flowers in both cases had the highest cytotoxicity. Plant extracts in both regions did not show significant cytotoxicity on normal HEK293 cells. Conclusion: The extract of the sagebrush plain region of Khorasan region showed greater cytotoxicity than Esfahan. It seems that different environmental conditionshas considerable cytotoxicity. Keywords: Sagebrush Plain, MTT, Breast Cancer}, Keywords = {Keywords: Sagebrush Plain, MTT, Breast Cancer}, volume = {18}, Number = {3}, pages = {241-251}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-359-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-359-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Solouki, M and PirhayatI, B}, title = {Fiberoptic Bronchoscopy in Diagnosis of Pleural Malignancy}, abstract ={Abstract Background & aim: Malignant pleural effusion is a common complication. Fiberoptic bronchoscopy is a procedure that allows direct visualization and provides biopsy of the injury. The purpose of the current study was to determine the efficiency of Fiberoptic bronchoscopy in the diagnosis of pleural malignancy. Methods: In the present study, fifty-two patients with exudative pleural effusion with unknown origin due to hemoptysis, atelectasis or wide effusion without large displacements mediastinum, and Endobronchial lesions were studied. Patients were investigated under local anesthesia, using fiberoptic bronchoscopes and the findings were recorded. Moreover, washing, microbial sampling and biopsies were conducted. The gathered data were analyzed by the Chi-square test. Results: Using Fiberoptic bronchoscopy in 22 patients (42.3%) led to the diagnosis of the underlying cause of pleural effusion. In cases of blood sputum, the possibility of which fiberoptic bronchoscopy could reveal the cause of pleural effusion was significantly high (p=0.04), but fiberoptic bronchoscopy did not play a major role in the diagnosis of both large effusion and atelectasis. Conclusion: If fiberoptic bronchoscopy is conducted on patients with hemoptysis to evaluate malignant pleural effusion, it can help establish a diagnosis, but is not recommended routinely for these patients. Key words: Fiberoptic Bronchoscopy, Pleural Effusion, Exudate}, Keywords = {Key words: Fiberoptic Bronchoscopy, Pleural Effusion, Exudate}, volume = {18}, Number = {2}, pages = {84-94}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-364-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-364-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Azizi, S and SadrzadehYeganeh, H and Hosseini, SM and Ahmadi, A and DaneshiMaskooni, M and Safarpour, M and Najibi, N}, title = {Food Insecurity and some Associated Socioeconomic Factors Among Women with Metabolic Syndrome Referred to Clinics of Shiraz University of Medical Sciences}, abstract ={Abstract Background & aim: Food insecurity is defined as limited availability at all times to sufficient food of an active life. The aim of this study was assessing the food insecurity status and some associated socioeconomic factors in women with metabolic syndrome. Methods: The present cross-sectional study was conducted on 130 women between 30-60 years of age with metabolic syndrome referred to health centers of Shiraz University of Medical Sciences in 2011. Demographic and socioeconomic characteristics and food insecurity status were assessed using demographic and the 18-item Agriculture Organization of the United States of America household food security questionnaires, respectively. Data were analyzed by Chi-square, t-tests and Logistic Regression statistical tests. Results: Prevalence of food insecurity in the population was 69.2%. Logistic regression showed the independent variables affecting food insecurity in women with metabolic syndrome were household economic status, family size, and income respectively (P<0.05). Conclusion: Due to high rate of food insecurity in women with metabolic syndrome, perhaps reducing food insecurity is associated with reduced metabolic syndrome. Therefore, it is necessary to reduce food insecurity in the society, especially among women. Key words: Food Insecurity, Metabolic Syndrome, Women}, Keywords = {Key words: Food Insecurity, Metabolic Syndrome, Women}, volume = {18}, Number = {2}, pages = {95-106}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-366-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-366-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Nikrooze, L and JafariBarmak, M and Naghmachi, M and Ghafarianshirazi, H and Dehghani, N}, title = {Study of Jaft Aqueous Extract and Silver Sulfadiazine on Burn Healing in Male Rat}, abstract ={Abstract Background & aim: Burns may lead to short-term or long term disability of victims and make the skin look inappropriate. Attention has been drawn to the plants containing tannins for the treatment of burn wounds. The purpose of this study was to compare the effect of aqueous extract of oak with silver sulfadiazine on burn wound healing in rats. Methods: In this experimental study, 60 male Wistar rats were randomly divided into 5 groups. 24 hours post-burn level 2 Silver sulfadiazine cream was treated for the first group and aqueous extract of oak at 1, 4, 7% were used for the second, third and fourth groups the control group was treated with physiology serum. After 30 and 60 days, mice were anesthetized and damaged skin tissues were removed and then transferred to 10% formalin. After histological processing and hematoxylin and eosin staning, the structure of the skin was examined by light microscopy. Data were statistically analyzed using ANOVA and Turkey. Results: Thickness of the epidermis, dermis, and the burns extract pairs, in groups of 1%, 4%, 7% in comparison to silver sulfadiazine showed a significant increase (P <0/05). Conclusion: It seemed that the 1% Sulfadiazine Cream compared with oak extract inhibited healing of the skin. Key words: Burn, Jaft (oak) extract, silver sulfadiazine, rat}, Keywords = {Key words: Burn, Jaft (oak) extract, silver sulfadiazine, rat}, volume = {18}, Number = {2}, pages = {107-114}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-368-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-368-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {AmidiMazaheri, M and Hosseini, M}, title = {Locus Of Control And General Self-Efficacy In Students Of Isfahan University Of Medical Sciences}, abstract ={Abestract Background & aim: Locus of control and general self-efficacy are important variables that have attracted the attention of researchers from various fields in the past three decades. The Aim of this study was determining the role of inhibition and general self-efficacy among the students of Isfahan University of Medical Sciences. Methods: In the present cross-sectional study, a total of 737 students from Isfahan University of Medical Sciences were randomly selected .Then, the Rotter Locus of Control and Self-Efficacy Questionnaire was filled by them. Data were analyzed by descriptive and inferential statistics t-test and also Pearson correlation analysis was performed. Results: About 47 percent of students were standing of external inhibition. General self-efficacy scores were significantly higher among boys than girls (p< 0.05). A number of 483 (65.5%) of the students said that the holding of self-education courses were necessary. Conclusion: Considering the importance of internal control to health care providers and since a high percentage of students were standing outside control, it is necessary to improve self-efficacy and changes in outside control to inside control, trainings courses especially for female students will be held. Key words: Self Efficacy, Locus of Control, Student, Isfahan University of Medical Sciences}, Keywords = {Key words: Self Efficacy, Locus of Control, Student, Isfahan University of Medical Sciences}, volume = {18}, Number = {2}, pages = {115-125}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-370-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-370-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Kafi, SM and Karimi, T and Farrahi, H}, title = {Study of Attention Deficit in Patients with Schizophrenia and Bipolar Disorder}, abstract ={Abstract Background & aim: Attention deficit has significant effect on the life of patients suffering from schizophrenia and bipolar disorder. The aim of this study was to assess the attention deficit in patients with schizophrenia. Methods: In the present post-hoc study, 132 patients with schizophrenia and bipolar disorder were selected via non-randomized sampling at Shafa Hospital (Rasht, Iran) and then divided into four equal groups: chronic schizophrenia patients, first-episode patients, chronic bipolar patients, and first-episode bipolar patients. Thirty-three healthy individuals were selected as the control group. Subjects were evaluated by Stroop color-word test. The gathered Data were analyzed by one-way ANOVA. Results: Attention deficit among chronic schizophrenics and patients suffering from bipolar disease was higher than the control group (p <1). Chronic schizophrenic patients compared with schizophrenia bipolar disease and first round schizophrenia showed more attention deficit. There was no significant difference among the first bipolar disease and schizophrenia, bipolar disorder, as well as the first round schizophrenia (p<0.05). Conclusion: Attention deficit is more severe in schizophrenic patients than bipolar disorder, and chronicity is more effective in schizophrenic patients. Key words: Attention, Schizophrenia, Chronicity}, Keywords = {Key words: Attention, Schizophrenia, Chronicity }, volume = {18}, Number = {2}, pages = {126-136}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-371-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-371-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Fazli, R and Nazarnezhad, N and Ebrahimzadeh, MA and Zabihzadeh, M}, title = {Evaluation of the Antioxidant capacities and Total Phenolic Contents of beech and oak Barks}, abstract ={Abstract Background & aim: Anti-oxidant compounds prevent prevalence of chronic diseases and food spoiling. The aim of this study was to evaluate the total phenolic and flavonoid content and antioxidant activity of beech and oak barks. Methods: In this experimental study, the skin of beech and oak trees were prepared and then acetone extraction was obtained using Soxhle method. At the beginning, total phenol and flavonoid of extracts were determined and the anti-oxidant properties of the extracts were then evaluated by three methods (methods Biphenyl Pykryl Hydrosol, regenerative power produced- and nitric oxide). Results: The amount of phenolic was higher in bark of beech trees, but flavonoids were higher in oaks. The result of test to trap free radicals of Biphenyl Pykryl Hydrazyl showed the inhibitory concentration 50% of acetone extract of the bark of beech and oak, were 92.19 and 33.7 mg/L respectively. Beech extracts had greater regenerative power than oak. In Nitric oxide trap test acetone extract inhibited 50% in bark of beech trees was 98/23 and the oak extract was 92/90 mg/L respectively. Conclusion: Acetone extract of the bark in three models showed varying degrees of anti - oxidant activity. Beech extract had better antioxidant activity compared with oak extract. Key words: Anti-oxidant Activity, Phenols, Flavonoids, Beech, Oak}, Keywords = {Key words: Anti-oxidant Activity, Phenols, Flavonoids, Beech, Oak}, volume = {18}, Number = {2}, pages = {137-145}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-372-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-372-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Salari, H and Esfandiari, A and Ostovar, R and Keshtkaran, A}, title = {Developing Appropriateness criteria for MRI of Low Back Pain(LBP) using Rand Appropriateness Method (RAM)}, abstract ={Abstract Background & aim: MRI is a new and expensive diagnostic technology which has been increasingly used globally. This aim of study was to determining the administration of MRI for the Lumbar vertebrae using the appropriate RAND Method. Methods: This qualitative study was based on consensus. The population study included 9 professionals involved in prescribing the procedure based on Rand. Two criteria were identified: Valid clinical guidelines and expert opinion. Scoring criteria were the numbers 1 to 9. Numbers in the range of 1 to 3 unfit, 4 to 6, unreliable, and 7 to 9, placed in an appropriate range. An agreement was done when 7 specialists agreed marked the same range. Results: 97 scenarios were selected for the lumbar spine MRI in the extracting phase. 18 other scenarios were added by panel members. Finally, a total of 115 scenarios were identified. After implementing two rounds, the scenarios were categorized into three ranges. Sixty eight (%59.1) of the scenarios were considered as appropriate, 44(%38.2) as uncertain, and 3(%2.6) as inappropriate. Conclusion: A developed scenario in this project for MRI lumbar vertebrae treated with Guide is perfect for specialists. It is recommended that insurance companies and other institutions use this as a benchmark for the payment of MRI lumbar vertebrae fees. RAND appropriateness Method is useful for identifying stakeholder views in settings with limited resources. Key words: Lumbar Spine, Low Back Pain, RAND Appropriateness Method}, Keywords = {Key words: Lumbar Spine, Low Back Pain, RAND Appropriateness Method }, volume = {18}, Number = {2}, pages = {146-155}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-373-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-373-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Nilsaz, Z and Babapour, R and Riahi, F}, title = {Risperidone Side effect in a Child with Autism and Suspected Dysphagia}, abstract ={Abstract Background & aim: Autism is one of the diseases with clearly associated disorders. Children with autism are not able to express the pain and in case of signs of mental disability in children a delay in reporting of diagnosis or misdiagnosis will occurs. The aim of this study was to report a case of risperidone in children with autism and suspected dysphagia. Case Presentation: This case report dealt with a rare complication of Risperidone side effect diagnosed as dysphagia in an autistic child. Risperdal is approved for autism treatment and the common side effects of this drug is increased appetite, but has led to difficulty in eating in children. To investigate the cause of dysphagia, no para-clinic examination was conducted. Conclusion: It is necessary to take a complete drug history in patients with problems of communication and swallowing disorders. Key words: Risperidone, Autism, Dysphagia, Child}, Keywords = {Key words: Risperidone, Autism, Dysphagia, Child}, volume = {18}, Number = {2}, pages = {156-162}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-374-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-374-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Rajaei, M and Noorian, K and Madineh, and Madineh, S}, title = {Comparing the Efficacy and Adverse Effects of Tramadol and Sodum Diclofenac with pethedine in the Treatment of Renal Colic}, abstract ={Abstract Background & aim: One of the choice treatments for pain relief in acute renal colic is administration of narcotics, but always the need for low-dose effects are felt difficulties. The aim of this study was to compare the efficacy of sodium diclofenac and pethedine hydrochloride with Tramadol to reduce the pain of acute renal colic. Methods: In this clinical trial study, 150 patients (15-65 years) with acute renal colic referred to Kashani hospital in Shahrekord were selected. The patients were randomly divided into 3 groups. The first group received 50mg tramadol intramuscular, the second group received 75mg D sodum iclofenac intramuscular and the third group (the evidence group) received 50 mg pethidin intramuscular. The pain severity was assessed before and then at 15, 30,60minutes after drug administration based on the McGill questionnaire. Data were analyzed with chi-square tests, ANOVA and Kruskal-Wallis tests. The pain severity of all parties on arrival to emergency ward and prior to the drug administration, and then 15, 30 and 60 min after the start of treatment were measured using a modified McGill questionnaire. Results: After drug administration (30.15 and 60 min), pain severity were decreased in all three groups. Minimum pain was seen in control where as the maximum pain was seen in tramadol group. Diclofenac have less side effects than pethedine (P<0.05). Conclusion: The finding showed that intramuscular Na Diclofenac due to its less adverse effects and more efficacy than tramadol is a suitable alternative to pethedine in treatment of acute renal colic. Key words: Pethedine, Tramadol, Diclofenac Na, Renal Colic}, Keywords = {Key words: Pethedine, Tramadol, Diclofenac Na, Renal Colic}, volume = {18}, Number = {1}, pages = {1-9}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-377-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-377-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Shanazari, Z and Marandi, SM and Samie, S}, title = {Effect of 12-Week Pilates Trainning on EDSS in Women Suffering fromMultiple Sclerosis}, abstract ={Abstract Background & aim: Multiple sclerosis is a debilitating disease that strikes the immune system. Multiple sclerosis is a chronic disease which debilitates the nervous system. The study was evaluated the effects of Pilates exercise on women with physical disabilities suffering from multiple sclerosis for 12 weeks .The aim of this study was to investigating the effects of Pilates trainning on EDSS of women suffering from Multiple Sclerosis (MS) for 12 weeks. Methods: In the present clinical trial study, 38 patients age 20-40 years (mean disease duration of 8±2 years) with multiple sclerosis grade 0-4.5 were selected. The Patients were randomly divided into two groups: experimental and control groups. The training program for pilates, 12 weeks, three sessions a week, with each session consisting of 60 minutes. Patients' physical disability was measured using Krutzke Expanded Disability Status Scale, before and after exercise. Data were analyzed by ANCOVA test. Results: Physical disability scores before and after the exercise in intervention was 47.1 and 37 and in the control group, was 93.1 and 43.1 respectively, which was significantly different in the intervention group before and after training (p<0.05). Conclusion: Pilates training improves the physical disability of MS patients. Therefore, this exercise can be used as a complementary treatment alongside drug treatments. Key Words: Multiple Sclerosis, Women, Pilates, EDSS}, Keywords = {Key Words: Multiple Sclerosis, Women, Pilates, EDSS }, volume = {18}, Number = {1}, pages = {10-18}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-379-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-379-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Nabiuni, M and Nasri, S and Poyanmanesh, F and Nazari, Z}, title = {Effect of Bumble Bee Venom in the Treatment of Polycystic Ovary Syndrome, the Relationship Between Tissue Factor Affecting the Level of TNFα in the Wistar Rat Model}, abstract ={Abstract Background & aim: Polycystic ovary syndrome (PCOS) is an endocrine failure leading to anovulation. TNFα is an effective factor in the regulation of normal functioning of the ovaries. High levels of TNFα causes PCOS is further. In this study, the effects of bumble bee venom (HBV) on TNFα and other symptoms of ovarian PCOS were studied. Methods: In this experimental study, 60 female Wistar rats were divided into three groups: control, sham and experimental groups. The experimental group was injected with estradiol valerate-induced PCOS direction. Induced rats (PCOS) were divided into two groups and treated with HBV. The treatment Group received 0.2mg of HBV for 10 consecutive days. Serum and ovarian tissue was collected from each of the four groups to compare the histological and changes in blood sugar levels. Results: A significant increase in ovarian PCOS weight was observed in the control group , whereas in the treated group with HBV rate fell (15.5 mg) Glucose levels in PCOS was 256.5, the control group138, and the treatment group 158. Thickness of the theca layer of antral follicles in the treated group compared with PCOS showed a significant decrease (110 μm and 150 μm respectively). Immunohistochemical results showed increased TNFα factor in PCOS group than in the control group, whereas these levels in samples treated with HBV Reduced. Conclusion: The results of this study revealed that the beneficial effects of HBV in PCOS may be due to the inhibitory effect on factor TNFα. Key words: Polycystic ovary syndrome, Bumble bee venom, Tumor necrosis factor, Immunohistochemistry}, Keywords = {Key words: Polycystic ovary syndrome, Bumble bee venom, Tumor necrosis factor, Immunohistochemistry }, volume = {18}, Number = {1}, pages = {19-31}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-380-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-380-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Izadi, Z and ModarresSanavi, SAM and Sorooshzadeh, A and Esna-Ashari, M and Davoodi, P}, title = {Antimicrobial activity of chamomile (Matricaria chamomilla L.) and feverfew (Tanacetum parthenium L.)}, abstract ={Abstract Background & aim: The essential oil of chamomile (Matricaria chamomilla L.) and feverfew (Tanacetum parthenium L.) are frequently used in pharmaceutical and cosmetic industries. The aim of this study was to investigate the antimicrobial effect of the essential oils of chamomile and chamomile and feverfew. Methods: This experimental study was conducted in 2012 at Hamedan University of Medical Sciences. Essential oils of two medicinal plants species including chamomile and feverfew were obtained by hydrodistillation their constituents were analyzed by GC and GC/MS using retention indices and fragmentation patterns. The antimicrobial effects (MIC and MBC) of the essential oils were assessed on a number of microorganisms including gram positive and gram negative bacteria by microdilution technique. The interaction of plant essential oils against microorganisms through differential inhibition index was also evaluated. Data were analyzed by Duncan's multiple range test statistic Results: The minimum inhibitory concentrations of the oils were 0.22-4 and 0.09-1 mg/mlfor chamomile and feverfew respectively. Moreover, the combination of the plants essential oils confirmed synergistic against L. monocytogenes, B. subtilis and B. cereus and additive activities against S. aureus, E. coli and S. typhimorium. Conclusion: The results of this study showed that the application of these essential oils is recommended in combination as an efficients and complementary method for controlling microorganisms. Key words: Chamomile, Feverfew, Antimicrobial Effect}, Keywords = {Key words: Chamomile, Feverfew, Antimicrobial Effect }, volume = {18}, Number = {1}, pages = {31-43}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-381-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-381-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Karimian, M and Pourahmadi, M and Jelodar, GA and Mehrab, F and Mohammadi, Z}, title = {The Effect of Atorvastatin on the Pancreatic Tissue of Male Rats}, abstract ={ABSTRACT Background & aim: Statins are inhibitors drugs of hydroxymethyl glotaryl coenzyme A. In addition to decreasing plasma cholesterol, low-density cholesterol they reduce the rate of triglycerides. The aim of this study was to investigate the effect of atorvastatin on rat pancreatic tissue.In addition to decreasing the rate of plasma cholesterol concentration they also decrease the rate of LDL and Triglyceride. The aim of this study was to investigate the effect of atorvastatin on rat pancreatic tissue. Methods: In this study, 32 adult male rats were divided into four groups, control and three test groups. To conduct the present study, 32 male adult rats were divided into 4 equal groups: one control group and three test groups. Then the test groups were treated by Atorvastatin for 45 days with 10mg (group1), 20mg (group2) and 30 mg (group3) doses respectively. At the end of the treatment period, all rats were killed by taking blood from their hearts. The pancreas tissue of each rat (N=32) was separated. After fixation, tissue preparation and slide staining, Longerhans diameter was measured and number of cells was counted. Data were analyzed by t test.After fixing and coloring the tissue, all slides were prepared and evaluated under the microscope the diameter of I's of Longerhans and the number of cells. The data was analyzed through t-test. Results: There was no significant difference in the diameter mean of Longerhans between the test groups and the control group. The mean number of islets cells were increased in compared to the control group (P>0.05).There was also a significant increase was shown in the number of Longerhans cells in the test groups in relation to the control group (p (05/0>.(p>0.05). Conclusion: The consumption of the atorvastatine causes an increase in the number of Longerhans cells. In addition, the increase in the number of cells also increases the insulin secretion. As a result, blood sugar is decreased. Key Words: Atorvastatin, Pancreas, Rat}, Keywords = {Key Words: Atorvastatin, Pancreas, Rat}, volume = {18}, Number = {1}, pages = {44-49}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-382-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-382-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Shahrivar, T and Moazedi, AA and Rasekh, AA and Almasi-Turk, S and Razmeh, S and Roozbehi, A}, title = {The Effects of Intrahippocampus Injection of Almond oil on Passive Avoidance Learning and Memory in Adult Male Rat}, abstract ={Abstract Background & aim: Almond oil contains compounds such asoleic acid, omega 3, 6, 9 polyunsaturated fatty acids and vitamin E. The aim of this study was to investigate the effects of intra-hippocampal injection of almond oil on passive avoidance learning and memory in male rats. Methods: In this experimental study, 56 male rats were randomly divided into 8 groups, including a control, 3 sailin groups which received normal saline 0.5, 1, 2 µl and 4 peanut oil groups which received 5/0, 1, 5/1 and 2 µl of oil.All groups, except the control, Groups except the control group were cannulated with stereotaxic surgery in the left CA1 region. One week after recovery, all groups were trained by shuttle box. Immediately after training, different doses of almond oil and saline were injected through the cannula in CA1 of hippocampus. After 48 hours, their Passive avoidance memory and learning were evaluated. Data were analyzed by ANOVA. Results: Almond oil doses of 0.5,1, 1.5 and 2 µg significantly improved passive avoidance learning and memory (P<0.05), but saline did not have. Conclusion: Almond oil as a steroid, effects on learning and memory and can improve learning and memory. Key Words: Learning, Memory, Almond oil, Hippocampus and Shuttle Box}, Keywords = {Key Words: Learning, Memory, Almond oil, Hippocampus and Shuttle Box}, volume = {18}, Number = {1}, pages = {50-60}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-383-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-383-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Khodadadi, P and Kargar, M and MoshfeaAA, AA and Ansari, H}, title = {Prevalence of rotavirus in children hospitalized with acute gastroenteritis in Imam Sajjad Hospital of Yasuj, 2011}, abstract ={Abstract Background & Aim: Rotavirus infection is the most common cause of dehydrating and gastroenteritis among children worldwide. . The aim of this study was to determine the prevalence of rotavirus in children hospitalized with acute gastroenteritis in Imam Sajjad Hospital of Yasuj. Methods: This cross sectional – descriptive study was done on 184 stool samples of children younger than 7 years of age hospitalized at Imam Sajjad hospital of Yasuj in 2011 due to acute gastroenteritis. All samples were routinely analyzed for detection of rotavirus by Enzyme Immunoassay (EIA) test. Data was analyzed by SPSS version 16, Chi-square test and Fisher's exact test. Results: Of the 184 samples analyzed, 52(28.26%) were positive.The Results showed significant relationship between the seasonal distribution and virus detection (p=0/001). The highest incidence of rotavirus was seen in autumn with frequency of (48.08%) and the lowest in spring (5.77%). Conclusions: According to high prevalence of rotavirus infection, continual surveillance is necessary to provide useful data for formulating effective vaccines and perform diarrhea prevention programs. Key words: Rotavirus, Gastroenteritis, Prevalence, Elisa}, Keywords = {Key words: Rotavirus, Gastroenteritis, Prevalence, Elisa}, volume = {18}, Number = {1}, pages = {61-68}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-384-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-384-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Ilami, O and Zareie, Z and Hadinia, A and Saeedinejad, SZ}, title = {A Case Report of a Patient with Leptospirosis}, abstract ={Abstract Background & aim: Leptospirosis is a zoonosis of worldwide distribution. One of the most important diseases common to man and animals. The aim of this study was to report a case of a patient with leptospirosis. Case Report: A 32 year old man from the southern tropical city of Kangan due to high fever, muscle pain, eye redness, enlarged liver and spleen voltage and the physical examination, slight yellowing of the conjunctiva was referred to Shahid Beheshti Hospital of Yasuj. Initial treatment of the patient's fever and flu-like symptoms before the test was ordered by physicians with antibiotics and patients' vital signs such as fever were controlled. After testing many different diseases and suspect cases, leptospirosis was confirmed. Conclusion: There is a risk of leptospirosis in presence of rodents in tropical vector and also the ecological conditions. When flu-like symptoms, enlarged liver and spleen, jaundice and symptoms of kidney involvement disease and failure to respond to conventional treatments exist, suspected cases of leptospirosis should not be missed and therefore better diagnostic tests should be conducted. Keywords: Leptospirosis, Animal, Febrile, Flu}, Keywords = {Keywords: Leptospirosis, Animal, Febrile, Flu }, volume = {18}, Number = {1}, pages = {69-75}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-385-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-385-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Moghaddasi, F and Haghshenas, MR and Naeimi, S}, title = {Polymorphism in CCR4 Gene (1014 C/T) in Patients with Breast Carcinoma from the South of Iran}, abstract ={ABSTRACT Background & aim: CCR4 gene polymorphism at position C/T1014 has been associated with changes in mRNA stability and is involved expression of this molecule. The aim of this study was to investigate CCR4 gene polymorphism at position 1014 C/T in breast carcinoma patients in southern Iran. Methods: In this case-control study, 150 women with breast carcinoma and 160 healthy women as controls were included. PCR-RFLP method was used to genotyping of CCR4, receptor gene. The data were analyzed using chi-square and Fisher. Results: Genotype frequencies of CC, CT and TT, in case group were 57.8, 35.1 & 7.1%, where as in control group showed 54.4, 39.4 & 6.2% respectively. In addition, C and T allele of the cases were, 75.3 & 24.7% and in control group 74.1 & 25.9% respectively (p>0.05). Conclusion: CCR4 gene polymorphism has no role in increasing of susceptibility to breast cancer in the south of Iran population. Key words: Polymorphism, CCR4, Breast cancer}, Keywords = {Key words: Polymorphism, CCR4, Breast cancer}, volume = {18}, Number = {1}, pages = {76-86}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-386-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-386-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Nikseresht, M and Rasti, T and JafariBarmak, M and GhasemiHamidabadi, H and Rezaei, Z and Dehghani, F and Mahmoudi, R}, title = {In Vitro Maturation and Embryo Development to blastocyst Mouse Germinal Vesicle Oocytes after Vitrification}, abstract ={Abstract Background & aim: Vitrification is a simple and ultra rapid technique for the conservation of fertility. Improving pregnancy rate associate with the use of cryopreserved oocytes would be an important advanced in human assisted reproductive technology (ART). The purpose of this study was to evaluate survival, oocytes maturation and embryo development to the blastocyst stage after vitrification of oocytes germinal vesicle-stage and multi stage Methods: In the present experimental study, germinal vesicle oocytes with or without cumulus cells were transferred to vitrification solution containing 30% (v/v) ethylene glycol, 18% (w/v) Ficoll-70, and 0.3 M sucrose, either by single step or in a step-wise way. After vitrification and storage in liquid nitrogen, the oocytes were thawed and washed twice in culture medium TCM119, and then subjected to in vitro maturation, fertilization, and culture. Data analysis was performed by using One-way variance and Tukey tests. Results: Oocytes survival, metaphase 2 stage oocyte maturation, fertilization and embryo formed blastocyst in vitrification methods multistage were significantly higher than the single step procedure (P<0/05) Conclusion: The Germinal vesicle stage oocytes vitrified with cumulus cells and stepwise procedure had positive effect on the survival, maturation and developmental rate on blastocyst compared to oocytes without cumulus cell and single step procedure. Key words: Germinal Vesicle Oocyte, Blastocyst, Vitrification, Ethylene glycol}, Keywords = {Key words: Germinal Vesicle Oocyte, Blastocyst, Vitrification, Ethylene glycol}, volume = {18}, Number = {8}, pages = {590-602}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-447-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-447-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Safavi, F and Ebrahimi, P and Mighani, H}, title = {In Vitro Anti-Bacterial Activity of Root And Aerial Parts of Scrophularia Striata Bioss on Escherichia Coli, Staphylococcus Aureus and Bacillus Cereus}, abstract ={Abstract Background & aim: Due to the side effects of chemical drugs, the replacement of these drugs by natural compounds with antibacterial properties, such as plant extracts, has received much attention. The aim of this study was to evaluate the phytochemical constituents and antimicrobial properties of root and aerial parts of Scrophularia against E. coli, S. aureus and B. cereus in vitro. Methods: In the present study, the antimicrobial activity of different extracts of roots and methanol extract of aerial part the sequential, minimal inhibitory concentrations of bacteria, and minimal bactericidal concentrations of bacteria were determined against the bacteria of E.coli, S. aureus and B. cereus by using both the disk diffusion and the tube dilution method. DMSO was used as the negative control, whereas nalidixic acid and ampicillin were used as the positive control. The collected data was analyzed using the one-way ANOVA test. Results: The results revealed that the root and aerial parts of Scrophularia striata contain flavonoids, glycosides, saponins, tannins and terpenoids. The ethyl acetate and chloroform extracts of root showed no inhibition zone on the bacterial growth. Whereas, the methanolic extract of the root was the most effective against B. cereus with the inhibition zone of the bacterial growth ( 21 mm), followed by MIC and MBC 60 mg/ml 70 mg/ml respectively. The methanol extract of aerial parts had the lowest effect on E.coli Conclusion: The results of the present study revealed that the methanolic extract of root and aerial parts of Scrophularia striata has antibacterial effects, especially against B. cereus. Therefore, further research is needed to identify the different compounds, and also, attainment of new formulation of these components in this plant. Key words: Staphylococcus aureus, Escherichia coli, Bacillus cereus, Antimicrobial, Scrophularia striata.}, Keywords = {Key words: Staphylococcus aureus, Escherichia coli, Bacillus cereus, Antimicrobial, Scrophularia striata.}, volume = {18}, Number = {8}, pages = {603-614}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-456-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-456-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Modaresi, M and Pouriyanzadeh, A}, title = {Effect of Ocimum Basilicum Hydro Alcoholic Extract Against Pentylenetetrazole-Induced Seizure in Mice}, abstract ={Abstract Background & aim: Epilepsy is one of the most common neurological disorders has always been considered. Despite the using of various drugs a number of patients are still drug-resistant. Osmium basilica was used in traditional medicine in the treatment of epilepsy and antiepileptic effects of this drug have been reported. The aim of this study was to evaluate the anticonvulsant effects of hydroalcoholic extract of Osmium basilicum in animal seizure models in mice. Methods: In this experimental study, 48 mature female mice were divided into 6 groups. The Hydro alcoholic extract of basil was prepared and then diluted with saline. Experimental groups included control, placebo and four treatments. 65 min before the injection of the Pentylenetetrazole all groups were received 100, 250, 300 and 350 mg/kg of extract intraperitoneally. The factors of seizure symptoms and signs were assessed. Data Tukey, Duncan were analyzed by ANOVA. Results: treated Group with 100 mg/kg of extract showed the highest seizure. Two groups treated with 100 and 250 mg/kg compared with the other groups had the highest and lowest incidence of myoclonic contractions respectively. 65 min before PTZ injection, the group treated with 250 mg/kg of extract showed a number of seizures and the mortality and morbidity rate increased and reduced significantly (p<0.05). Conclusion: The results can be obtained at a dose of hydro alcoholic 250 mg/kg effective as medication in preventing seizures in animal models introduced. The hydroalcoholic extract of Osmium basilica at dose of 250 mg kg proposed as an effective medication to prevent seizures in animal models. Key words: Epilepsy, Seizure, Ocimum basilicum , Pentylenetetrazole}, Keywords = {Key words: Epilepsy, Seizure, Ocimum basilicum , Pentylenetetrazole}, volume = {18}, Number = {8}, pages = {615-621}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-457-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-457-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Mohammadinasab, M and Khosravani, A and Kafilzade, F and Jahangirisisakht, A and Mohammadi, R and Abasi, R}, title = {Prevalence of Bordetella Pertussis, and Legionella Pneumophila in Patients with Pneumonia Diagnosis in Shahid Beheshti Hospital by Culture and Multiplex PCR}, abstract ={Abstract Background & aim: Respiratory pneumonia is a common infection which interferes with several cases. The aim of this study was to determine the incidence of B. pertussis, and Legionella pneumophila in patients diagnosed with pneumonia in Shahid Beheshti Hospital by Multiplex PCR and culture. Methods: In this experimental study, after finding patients and completing the questionnaires, 126 samples of sputum were collected from the patients. The samples were transported to the laboratory and divided in two parts. Approximately 1 ml of the samples were used for Multiplex PCR and the remainder were used for culture and Gram stain immediately. Data were analyzed using chi square tests. Results: Out of the 126 samples, 35.7 %were male, 64% were female, and the mean age was 44 years. The culture results of B.pertussis and L.pneumophila were negative. However, the results of PCR showed that L.pneumophila in 13 patients (10%) and B.pertussis in one patient (0.8%) were detected respectively. Conclusion: Due to positive results obtained in this study, the importance of pneumonia caused by these bacteria can be realized in the research area. As the PCR is one of the rapid methods for the diagnosis of pneumonia. Use of this technique can have good results in the treatment of pneumonia before wasting time. Key words: B.pertussis, L.pneumophila, PCR, Respiratory Pneumonia}, Keywords = {Key words: B.pertussis, L.pneumophila, PCR, Respiratory Pneumonia}, volume = {18}, Number = {8}, pages = {622-631}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-460-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-460-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Najafian, m and مسیحی, s and Zargar, m and khosravi, p}, title = {Estimation of fetal weight according to femur length and abdominal circumference and compared with actual birth weigh}, abstract ={Abstract Background & aim: The high incidence of deaths during delivery, is related to infant’s weight and problems linked to it. The estimation of fetal weight in managing of labor and delivery is very important. This study were compared the estimated fetal weight, abdominal circumference , femur length and birth weight by ultrasound in pregnant women. Methods: This cross - sectional study was performed on 600 pregnant women who delivered singleton pregnancies referred to care during the years 1390 to 1391 in Imam Khomeini's Iran 72 hours before delivery. Patient data included gestational age, past medical history, estimated fetal weight, abdominal circumference and femur length and prenatal based on Hadlock equation and the neonatal weight was recorded. In case of non-delivery within 72 hours, the patient was excluded. Pearson correlation and chi-square test was used to compare proportions. Results: Pearson correlation coefficients between weight estimate before programming the birth (0.878) and the actual weight at birth date, the weight under 2500 g,( 0.888), group weighing between 2500 to 4000 g, (0.816) and the group weighing more than 4000 g, (0.399) were measured. The mean absolute difference tof estimated weight and the actual weight before birth, after birth were determined in total (96.174 g). The mean difference between the estimated weight and the actual weight after birth in SGA fetus (small for gestational age ratio), 88/172 mg, infants weighing between 4000-2500 g 29/175 g and 4000 g in weight, 213.46 mg were determined Conclusions: Validity of ultrasound 72 hours before delivery for fetuses weighing less than 4000 grams acceptable and for fetuses weighing 4000 g was relatively weak. Keywords: Estimated fetal weight,Actual weight after birth,Ultrasonography}, Keywords = {Keywords: Estimated fetal weight,Actual weight after birth,Ultrasonography}, volume = {18}, Number = {8}, pages = {632-640}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-461-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-461-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Porhemmat, f and Shariati, M and Sepehrara, L}, title = {Effect of Pistacia Vera Oil on Pituitary Gonad Axis and Histological Testis Changes in Adult Male Rats}, abstract ={Abstract Background & aim: Pistachio oil contains the chemical compounds such as saturated and unsaturated fatty acids. Saturated fatty acids can inhibit 5-α- reductase enzyme and unsaturated fatty acids increase cholesterol levels in the body. The aim of the present study was to determine the effects of pistachio oil on adult male rats’ reproductive status. Methods: In the present experimental study, 40 male Wistar rat were divided into five groups of eight. The control group received water and standard food the sham group received an equal of distilled water as a solvent and the experimental groups receiving 1, 2 and 4 ml/kg of pistachio oil for a period of 28 days orally. At the end of the 28th day, blood samples and preparation of tissue sections were taken from the rats. The results were analyzed by Excel, One- way analysis variance, and t- test. Results: The results of hormonal assays revealed that the pistachio Vera oil at 2 and 4 ml/kg, had a significant increase in testosterone levels (P <0.05) compared to the control and sham groups. Histopathological analysis showed that the sperm density in seminiferous tubules of the testis in experimental groups increased significantly (P <0.05). Conclusions: The pistachio Vera oil increased testosterone and tubular sperm density, possibly related with compounds such as palmitic and myrystic acids as the inhibitor of 5 - alpha - reductases and increased biosynthesis of 17 - beta hydroxysteroid dehydrogenase. Key words: Pistachio Vera oil, Testis, Gonadotropin, Testosterone, Rat}, Keywords = {Key words: Pistachio Vera oil, Testis, Gonadotropin, Testosterone, Rat}, volume = {18}, Number = {8}, pages = {641-649}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-462-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-462-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Porhemmat, f and Shariati, M and Sepehrara, L}, title = {Effect of Pistacia Vera Oil on Pituitary Gonad Axis and Histological Testis Changes in Adult Male Rats}, abstract ={Abstract Background & aim: Pistachio oil contains the chemical compounds such as saturated and unsaturated fatty acids. Saturated fatty acids can inhibit 5-α- reductase enzyme and unsaturated fatty acids increase cholesterol levels in the body. The aim of the present study was to determine the effects of pistachio oil on adult male rats’ reproductive status. Methods: In the present experimental study, 40 male Wistar rat were divided into five groups of eight. The control group received water and standard food the sham group received an equal of distilled water as a solvent and the experimental groups receiving 1, 2 and 4 ml/kg of pistachio oil for a period of 28 days orally. At the end of the 28th day, blood samples and preparation of tissue sections were taken from the rats. The results were analyzed by Excel, One- way analysis variance, and t- test. Results: The results of hormonal assays revealed that the pistachio Vera oil at 2 and 4 ml/kg, had a significant increase in testosterone levels (P <0.05) compared to the control and sham groups. Histopathological analysis showed that the sperm density in seminiferous tubules of the testis in experimental groups increased significantly (P <0.05). Conclusions: The pistachio Vera oil increased testosterone and tubular sperm density, possibly related with compounds such as palmitic and myrystic acids as the inhibitor of 5 - alpha - reductases and increased biosynthesis of 17 - beta hydroxysteroid dehydrogenase. Key words: Pistachio Vera oil, Testis, Gonadotropin, Testosterone, Rat}, Keywords = {Key words: Pistachio Vera oil, Testis, Gonadotropin, Testosterone, Rat}, volume = {18}, Number = {8}, pages = {641-649}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-463-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-463-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Nemati, P and Nooryan, K and Mahmodi, F}, title = {The Effect of Cognitive-Behavioral Counseling on Anxiety and Aggression Women with Sexual Dysfunction}, abstract ={Abstract Background and aim: According to the American Psychiatric Association female sexual dysfunction are classified in four categories: sexual desire disorders, arousal, orgasm and pain. Having chronic Sexual dysfunction can lead to anxiety, depression, aggression and create problems in other aspects of life. The aim of this study was to Investigate the effect of cognitive-behavior counseling on anxiety and aggression in women with sexual dysfunction. Methods: In this clinical trial, 20 women were referred to Taleghani Hospital in Tehran with anxiety and aggression of sexual problems selected to measure sexual satisfaction. Glombok Rust questionnaire was used to measured the sexual satisfaction and Spielberger Questionnaire 40-item for Anxiety and Buss and Mark Perry questionnaire for aggression. Data were statistically analyzed by t test. Results: in general, the mean total of sexual satisfaction decreased from 79.05 at pretest to 7.35 at posttest p <0.05). the mean pretest of physical aggression from 28.2 and verbal aggression from 17.3 and nervous aggression from 28.95 followed by the aggression of the enemy from 29.95, have declined in post test to 12. 55 , 7.8, 12.3, and 3/12 respectively ( p <0.05). the results of Spielberger questionnaire showed that the mean pre-test state and trait anxiety were decreased from 63 and 62.5 to 35.1 and 34.15 respectively (p <0.05). Conclusion: Cognitive-behavioral counseling may not only have a significant effect in reducing sexual dysfunction in women, but also a significant role in reducing anxiety and aggression as reactions with this disorder. Key words: Sexual Dysfunction, Anxiety, Aggression, Women}, Keywords = {Key words: Sexual Dysfunction, Anxiety, Aggression, Women}, volume = {18}, Number = {8}, pages = {650-660}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-464-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-464-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Jafari, F and Aminzadeh, M and Gitinavard, F}, title = {Assessment of Snacks Consumption among High School Students of Tehran during 2010-2011 Years}, abstract ={Abstract Background & aim: Eating snacks during the day can lead to energy distribution and improvement of the health status of students. The aim of this study was to assess the pattern of snack consumption among high school students in region 8 of Tehran. Methods: This descriptive cross sectional study was performed on 300 high school students in district 8 of Tehran educational board during 2010-2011. Cluster sampling was done as a random method. Data were collected by a researcher-made questionnaire. Data were analyzed using descriptive statistics and Spearman, Pearson and ANOVA. Results: The mean age of participants was 16.2±0.9. 64.6% of students ate snacks everyday and 10.1% of them didn’t use any snack at school. Most students (14.8%) ate sandwich as snack prepared by school’s buffet every day. Tea (12.4%), fruits (12%), cheese bread (10%) and home -made sandwiches (7.9%) were also used as snacks. Results showed that among food consumed as snack, sandwich consumption was negatively associated to the grade of previous semester. Moreover, the consumption of blowgun and cakes were increased in children with more educated fathers. Conclusion: Despite the fact that the consumption of snacks during school attendance is good in terms of quantity, but the quality and usefulness of food still need more attention Keyword: Snack, High school, Average, Student}, Keywords = {}, volume = {18}, Number = {8}, pages = {661-671}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-465-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-465-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Sabetian, G and Masjedi, M and Moradian, F and Nikeghbalian, Z}, title = {The importance of radiology in detection of complications associated with central venous catheter insertion: case report}, abstract ={Abstract Background & aim: One of the goals of central venous catheter (CVC) insertion is monitoring of fluid therapy, but the catheter insertion can be associated with several complications. The objective of this study was to determine the role of radiology in central venous catheter complications. Case presentation: 77-year-old woman, a known case of chronic lymphocytic leukemia due to deep vein thrombosis treated with warfarin and due to peritonitis is undergoing emergency surgery. After insertion of central venous catheters and receiving fresh frozen plasma to correct the clotting dysfunction, the candidate is transferred to the operating room. Once during Intraoperative and again immediately after entering the ICU were involved with ventricular arrhythmia. Chest x-ray showed massive unilateral hydrothorax. Conclusion: Most complications of central venous catheter is diagnosed on chest radiograph and appropriate treatment of these complications is tsaving. Key words: Central Venous Catheter, Hydrothorax, Radiography}, Keywords = {Key words: Central Venous Catheter, Hydrothorax, Radiography}, volume = {18}, Number = {8}, pages = {673-677}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-466-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-466-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Hashemi, F and ALipoor, A and Feili, A}, title = {The Effectiveness of Cognitive Behavioral Stress Management Therapy on Happiness among Infertile Women}, abstract ={Abstract Background & aim: infertility and the attitude of the society toward it, makes women and even men deal with many emotional disturbances. Infertile women tolerate more stress than fertile women. Stress can reduce the amount of happiness and mental health. The aim of this study was to investigate the effects of stress management skills training (cognitive-behavioral) on happiness of infertile women. Methods: In this clinical-trial study, the cases of infertile women who were referred to the Infertility Center of Shiraz in the summer of 2011were studied. A total of 24 infertile women with high stress scores were selected by purposive sampling and divided into two experimental and control groups. The stress management training (cognitive-behavioral) was instructed during 10 weekly sessions on the target group. Using Oxford Happiness Questionnaire, a pre-test and a post-test was completed. The data were analyzed by descriptive statistics and ANCOVA. Results: The difference between the mean happiness was significant after controlling of the pretest variables in the two groups. The mean scored happiness of the experimental group significantly increased compared to the control group in the post-test (P=0.0001). Conclusion: The results indicated that the control effectiveness of stress management therapy, cognitive behavioral therapy on happiness levels of infertile women. Key words: Happiness, Cognitive- Behavioral, Stress Management, Infertility}, Keywords = {Key words: Happiness, Cognitive- Behavioral, Stress Management, Infertility}, volume = {18}, Number = {9}, pages = {678-686}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-472-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-472-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Pirali-Kheirabadi, KH and Dehghani-Samani, A and Adel, M and Hoseinpour, F}, title = {The Effect of Essential Oil of Nigella sativa and Satureia hortensis on Promastigot Stage of Lishmania major}, abstract ={Abstract Background & aim: Leishmaniasis is a zoonotic disease caused by a protozoan parasite of the genus Leishmania. Traditionally, medicinal plants have been used for topical effects of leishmaniasis. The aim of this study was to evaluate the effect of the essential oil of Satureia hortensis and Nigella sativa on the Leishmania major. Methods: In this experimental study, the effects of the plant’s essential oils and savory black beans on the Leishmania major form were studied. Evaluation was determined based on the average of Leishmania parasites form survival after exposure to different concentrations of herbs and chemical drugs MA dose at different intervals. For this purpose, different extracts with ratios of 0.1, 0.2, 0.4, 0.8, 1.2, 1.6, and 2% were added. Different groups of this study were kept in the same condition (incubated at 26 ° C). The parasites were removed from the incubator and the numbers of viable parasites were counted after 24hours. Data were analyzed using descriptive statistics, Tukey test and GM. Results: There was a significant difference in reducing parasites on groups receiving Satureia hortensis and Nigella sativa with Glucantime (p <0.05). Conclusion: Due to the increasing drug resistance of Leishmania, plant oils such as Satureia hortensis and Nigella sativa could be used as an alternative treatment for controlling leishmaniasis. Key words: Essential oil, Leishmaniasis, Nigella sativa, Satureia hortensis}, Keywords = {Key words: Essential oil, Leishmaniasis, Nigella sativa, Satureia hortensis}, volume = {18}, Number = {9}, pages = {687-698}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-475-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-475-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Bonyadi, F and Nejati, V and Tukmechi, A and Hasanzadeh, SH and Riki, M}, title = {Evaluation of Apoptotic Effects of Cell Wall and Cytoplasmic Extract from Saccharomyces cerevisiae on K562 Cell Line}, abstract ={Abstract Background & aim: Probiotics are living microorganisms that have beneficial effects, such as anti-tumor effects on the health. The aim of this study was to evaluate the inhibitory effect of cell wall and cytoplasmic extracts of Saccharomyces cerevisiae as a probiotic cancer Category K562 (myeloid leukemia) and apoptotic effects of this yeast. Methods: In this experimental study, the Saccharomyces cerevisiae was cultured, and using the micro sonicator the cell wall and cytoplasmic extracts were separated. Then, different concentrations of cell wall and cytoplasmic extracts were prepared. The inhibitory growth percentage of cancer K562 cell line at different times (12, 24, 48 and 72 h) was measured by MTT assay. Apoptosis and necrosis were also evaluated by DNA fragmentation electrophoresis method. The collected dara were analyzed by ANOVA and Tukey test. Results: Anti-tumor activity of cytoplasmic extracts significantly increased over time, while the impact of anti-tumor activity of the cell wall over time was significantly reduced (p <0.05). The composition of the Saccharomyces cerevisiae also induces apoptosis, and less necrosis at K562 cell line. Conclusion: This study showed that the cell wall and cytoplasmic extracts of Saccharomyces cerevisiae in a time-dependent had an inhibitory effect on K562 cells and induced necrosis and apoptosis. Keywords: K562, S. Cerevisiae, Cell wall, Cytoplasmic Extract, Apoptotic Effects}, Keywords = {Keywords: K562, S. Cerevisiae, Cell wall, Cytoplasmic Extract, Apoptotic Effects}, volume = {18}, Number = {9}, pages = {699-710}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-478-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-478-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Razmi, M and Divsalar, A}, title = {The Effect of Β-casein Nanoparticles on Bioavailability and Cellular Uptake of Platinum Complex as a Cancer Drug}, abstract ={Abstract Background & aim: Due to the low solubility and high toxicity of drugs, treatment of cancers is problematic therefore, the encapsulation and targeted delivery of therapeutic effect is required. The aim of this study was to investigate the effect of nanoparticles on cellular uptake and bioavailability of beta-casein on platinum complexes as cancer drugs. Methods: In the present experimental study, the physicochemical properties of nanoparticles as drug carriers of beta-casein devices using dynamic light scattering (DLS) and scanning electron microscopy (SEM) were investigated. In order to evaluate the toxicity effects of platinum complexes, the colon cancer cells in the absence or presence of free platinum complex concentration and nanoparticle loaded with platinum complexes were incubated for 24 and 48 hours. LD50 Values (concentration of compound causing 50% mortality in the cells) was determined using the MTT assay. Data were analyzed by ANOVA and post-hoc test. Results: At a concentration of 1 mg ml, beta-casein nanoparticle drug carriers were synthesized in the range of 100 to 300 µM. In addition, the mortality rate in cancer cells by the release of platinum complexes (without and with the capsule), were 70 and 26 in 24 hours, and 60 µM and 21 µM in 48 hours respectively, Conclusion: The study showed that the bioavailability of the encapsulated platinum complexes increases and new drug delivery system may be a good candidate for the treatment of cancer. Key words: Beta-casein, Pt (II) Complex, Bioavalibility, Nanocarrier, Micelle}, Keywords = {Key words: Beta-casein, Pt (II) Complex, Bioavalibility, Nanocarrier, Micelle}, volume = {18}, Number = {9}, pages = {711-722}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-479-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-479-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Aghamollaei, H and AziziBarjini, K and MoosazadehMogaddam, M}, title = {Rapid Detection of Pseudomonas Aeruginosa by PCR Method Using Specific Primers of Quorum Sensing LasI gene}, abstract ={Abstract Background & aim: Pseudomonas aeruginosa is an opportunistic nosocomial pathogen that due to having intrinsic and acquired resistance to common antibiotics, mortality due to infections is very common. Therefore, early and accurate identification of bacteria could be effective in controlling infections and deaths. The aim of this study was to evaluate the use of a rapid method with high sensitivity and specificity based on polymerase chain reaction using gene-specific primers quorum sensing LasI system for detection of bacteria. Methods: In this study, the comparison between the results of culture and PCR for the diagnosis of Pseudomonas aeruginosa in clinical samples and other bacterial species were carried out. 40 strains of Pseudomonas aeruginosa from isolated clinical specimens were identified and confirmed by biochemical tests. LasI gene specific primers were designed using bioinformatics analysis. Sequence of this gene was amplified techniques after extraction of bacterial genome. The specificity of PCR tests with DNA from of different species, Staphylococcus aureus, Klebsiella pneumonia, Escherichia coli and Vibrio cholerae were evaluated. A different dilution of the bacterial genome of Pseudomonas aeruginosa was used in PCR to evaluate the sensitivity of primer. Data were analyzed by t-test Results: The results indicated that the PCR test result was positive for all strains of P. aeruginosa isolates however, PCR test results were negative for the four other bacteria. Even at 10-5 Pseudomonas aeruginosa genome concentration, PCR test was positive for all isolated strains Conclusion: This study showed that the primers designed for detection of Pseudomonas aeruginosa using PCR, had higher sensitivity and specificity compared to previous methods. Keywords: Pseudomonas aeruginosa, PCR, Quorum sensing, LasI}, Keywords = {Keywords: Pseudomonas aeruginosa, PCR, Quorum sensing, LasI}, volume = {18}, Number = {9}, pages = {723-735}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-480-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-480-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Nabavizadeh, SH and Yazdanpanah, SH and Abidi, H and Zoladl, M}, title = {The incidence of Common Allergens in Patients with Allergic Rhinitis Referred to Shahid Mofatteh Clinic, Yasuj, Iran}, abstract ={Abstract Background & Aim: Allergic diseases are one of the most common diseases which are more prevalent in certain seasons. The aim of this study was to determine the prevalence of respiratory and food allergies to common allergens in patients with allergic rhinitis. Methods: This cross-sectional study was performed on 184 patients including 120 males and 64 females referred to the Shahid Mofatteh Clinic with the respiratory allergy symptoms including rhinitis, sneezing and coughing during 2012-2013. Data collection, checklist registered, including demographic information and data associated with sensitivity of skin prick test of 21 allergens were selected. Data were analyzed using descriptive and inferential statistical. Results: A number of 153 patients (83.2%) were allergic to one or more of the 21 allergens tested, whereas 31 patients (16.8) of them showed no sensitivity. The most common allergic reactions to insect allergens were 73 cases (47.7%), grass and turf 58 cases (37.9% percent), Beetle 55 cases (35.9%), wheat flour, 51 (33.3%) walnuts, 37 (24.4%) and cat fur 36 (5/23.5%) respectively.. Conclusion: Susceptibility to insects, beetles and grass had the highest prevalence in patients with allergic rhinitis referred to Super Specialized clinic in Yasuj. Because susceptibility to allergens depends on the environment, therefore, being aware of them can lead to avoidance and control allergic reactions. Key words: Allergic Disease, Skin Prick Test, Rhinitis}, Keywords = {Key words: Allergic Disease, Skin Prick Test, Rhinitis}, volume = {18}, Number = {9}, pages = {736-745}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-481-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-481-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Paraham, G and Amin, MM and Ehteshami, M and Sadat, AM and Ebrahimi, A and Ehteshami, MG and Moradi, S}, title = {Determination of distribution pattern of the heavy metal concentrations in the potable network of Gachsaran by Geographical Information System (GIS)}, abstract ={Abstract Backgrounds & aim: The heavy metals entering the water resources through different channels pose risks, such as poisoning and carcinogenesis, in the living organisms’ body. The aim of this study was to determine the distribution pattern of heavy metals in drinking water networks using GIS in Gachsaran, Iran. . Methods: In this descriptive, cross-sectional study, samples were taken from11 spots of the drinking water distribution network and tested for concentration of 10 metals by Inductivity Coupled Ions Plasma (ICP) method in summer of 2010. The research data were compared with national and international water standards. Then the distribution map of heavy metals concentrations in the drinking water wells of the region was prepared by using the Geographical Information System (GIS) software. Data were analyzed by the Kruskal-Wallis tests. Results: In all samples, the average concentration of heavy metals were: Arsenic 0.54, Cadmium 0.05, Zinc 55.9, Lead 0.18, Copper .82, Chromium 1.6, Barium 36.5, Selenium0.5, Mercury 0.1 and Silver 0.05 micrograms per liter and was less than the water quality standard. Conclusion: Based on the results obtained, it can be concluded that concentrations of heavy metals in Gachsaran’s drinking water distribution network are not higher than national and international standards and therefore not harmful for people. Key words: Heavy metals, Distribution network, Gachsaran, geographical information system (GIS)}, Keywords = {Key words: Heavy metals, Distribution network, Gachsaran, geographical information system (GIS) }, volume = {18}, Number = {9}, pages = {746-756}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-482-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-482-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Parhizgari, N and Moosavian, SM and Sharifi, A}, title = {Antibiotic resistant pattern of methicillin resistant and sensitive Staphylococcus aureus isolated from patients durining 2009-2010, Ahvaz, Iran.}, abstract ={Abstract Background & aim: Staphylococcus aureus is one of the most important nosocomial infecting agents resistant to commonly used antibiotics. Nowadays, methicillin-resistant S. aureus (MRSA) is considered one of the main causes of nosocomial infections. The aim of this study was to identify the antibiotic resistance pattern of methicicllin- resistant and susceptible strains in Ahwaz, Iran. Methods: In the present cross - sectional study, a number of 255 clinically suspected cases of Staphylococcus aureus were collected during a 19 month period. The bacteria were investigated using standard biochemical tests such as catalase, mannitol fermentation, coagulase and Dnase. Sensitive strains were confirmed by disk diffusion method compared to commonly used antibiotics. The collected data were analyzed using descriptive statistical tests. Results: of 255 suspected cases, 180 were confirmed as S.aureus, a total of 59 strains of S. aureus (2/37 percent) were resistant to methicillin. Resistance to S. aureus strains resistant to methicillin included: chloramphenicol (3.38%), rifampin (45.76%), norfloxacin (89.83%), gentamicin (89.83%), ciprofloxacin, (91.52%), azithromycin, (88.13%), cotrimoxazole (86.44%) and all isolates strains were sensitive to vancomycin and nitrofurantoin. A total of 10 different patterns of antibiotic resistance in methicillin-resistant Staphylococcus aureus strains were identified. Conclusion: Expression of new resistance factor in nosocomial infection is one of the major challenges in treating these infections. This study showed a high prevalence of resistance against some class of antibiotics in MRSA isolated from Imam Khomeini and Golestan hospital of Ahwaz, Iran. Key words: Nosocomial infection, Methicillin Resistant Staphylococcus aureus (MRSA), Antibiotic Resistant Pattern}, Keywords = {Key words: Nosocomial infection, Methicillin Resistant Staphylococcus aureus (MRSA), Antibiotic Resistant Pattern}, volume = {18}, Number = {9}, pages = {757-767}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-483-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-483-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {ManouchehriNaini, K and Arefkhah, N and Mortezaei, S and Hossani, SA and Nosrati, V and Falahizadeh, S and Dehghani, F}, title = {Malaria situation in KOhgiloye and Boyerahmad province during 2001-2010}, abstract ={Abstract Background & aim: Islamic Republic of Iran is one of the well-known foci of malaria in Eastern Mediterranean Region.The study was carried out to investigate malaria situation in Kogiloye and Boyerahmad during during 2001-2010. Methods: The retrospective study using data information were extracted from health center of archived from malaria cases had been recorded in province during the years of 2001-2010 .The data were analyzed by Descriptive statistical test. Results: Out of one hundred and fifty six malaria cases during this decade, 119 (76.28%) were males and 37 (23.7%) females. The study showed that about 87% of malaria cases had been occurred in Afghanian immigrants in this region. The highest and lowest (29.6% vs.1.9%) rates of malaria were occurred in 2002 and 2010 , respectively. Among districts of the province the highest rate of malaria cases was belonged to Boyerahmad (80.1%).The present study indicated that Plasmodium vivax was the most common cause of malaria in this region ( 91.02%) followed by P.falciparum ( 8.33%). Conclusion: During the past decade malaria cases were apparently decreased in Kohgiloye and Boyerahmad province and most of cases had been imported to the region from other endemic foci. Respect to suitable environmental conditions for transmission of malaria in this area surveillance measures should be implicated to control disease through rapid diagnosis and treatment of patients particularly in foreign immigrants. Key words: Malaria, P.Vivax , P.Falciparum}, Keywords = {Key words: Malaria, P.Vivax , P.Falciparum}, volume = {18}, Number = {9}, pages = {768-776}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-484-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-484-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {FatemeyanRad, F and Mostanbt, N and Zoladl, M}, title = {The Effect of Training on Coping with Stress, Anxiety and Depression among Patients with Special Diseases}, abstract ={Abstract Background & aim: Lack of knowledge and fear of treatment, predisposes individuals to the occurrence and intensity of psychological reactions therefore it is necessary for people to learn appropriate coping strategies.The aim of this study was to determine the effect of education on coping with stress, depression, anxiety and stress among patients with special diseases. Methods: This clinical trial study was performed on 30 patients referred to Shahid Beheshti Hospital of Yasuj, Iran, as specific pre-test and post-test. The patients were divided into two groups randomly. Instruments used included specific questionnaires for depression, anxiety and stress Das 42 Lavybound, and a demographic questionnaire. A seven session period of instruction, each session an hour and a half, was held in coping with stress. The collected data was analyzed by Chi-square tests, t-dependent and-independent tests. Results: Before the intervention of two groups, no significant differences were seen in the levels of depression, anxiety and stress. But after intervention, significant differences were observed in the levels of stress (23.1 before the intervention to 17.5 post-intervention) and anxiety (15 pre-intervention to the 10.9 post-intervention) (P <0/05). Conclusion: The training procedure was effective in decreasing the stress and anxiety in particular diseases and could lead to a relative relief in depression patients. Key words: Special Patients Coping, Depression, Anxiety, Stress}, Keywords = {Key words: Special Patients Coping, Depression, Anxiety, Stress}, volume = {18}, Number = {9}, pages = {777-786}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-485-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-485-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2013} } @article{ author = {Khosravani, SR and Golkari, A and Memarpour, M}, title = {Assessing the Relationship between Dental Caries and Anthropometric Indices in 9-11-Year-old Primary School Children of Shiraz}, abstract ={Abstract Background and aim: Dental caries is the most prevalent chronic childhood disease that has a profound impact on the health of both the individual and community health. On the other, the overweight and underweight in children is a major public health concern influenced by common factors with dental caries. The aim of the present study was to assess the relationship between DMFT (Decay-Missing-Filled-permanent teeth) and anthropometry indices in 9-11 year old primary school children of the city of Shiraz, Iran-2012. Methods: The present cross-sectional study was conducted on primary school children, aged 9 to 11 years, selected by cluster random sampling in four areas of Shiraz city, in 2012. The prevalence of children with dental caries was calculated by measuring the number of teeth decayed, missing or filled duo to caries (DMFT) indices using the WHO screening standards. Weight, height, and sitting height were measured and body mass index (BMI) and leg height were calculated. The association between Anthropometry and DMFT were examined using bivariate correlation and linear regression tests by the SPSS software. The difference mean DMFT index between five groups of BMI was evaluated by ANOVA and post hoc Tukey tests. Results: A total of 974 pupils were studied. Mean DMFT was 0.94±1.46. There were significant association between DMFT and BMI (r=-0/91 p=0/005). Mean DMFT was significantly reduced from underweight children to obese children (p=0/027). Conclusion: Underweight children have a higher risk of developing caries in their permanent teeth. Key words: Body Mass Index, Anthropometry, DMF Index}, Keywords = {Key words: Body Mass Index, Anthropometry, DMF Index}, volume = {18}, Number = {10}, pages = {787-769}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-486-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-486-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2014} } @article{ author = {AkbariAliabad, S and Nabavizadeh, SH and Mossavizadeh, SA and Hadinia, A}, title = {Correlation between Serum Levels of Total IgE Antibody and Percent of Eosinophil Cells in Patients with Asthma Referred to Yasuj Mofatteh Clinic in 2013}, abstract ={Abstract Background & aim: According to the role of eosinophil cells and IgE antibody in the pathogenesis of asthma, the aim of this study was to determine the correlation between serum levels of total IgE antibody and the percentage of eosinophil cells in patients with asthma. Methods: This case - control study was performed on 30 patients with asthma referred toYasuj Mofatteh Clinic in 2013. The disease had been confirmed by relevant specialists as the case group and 30 healthy subjects were selected with no history of respiratory disease or infection parasitic diseases as controls. After completing the questionnaire included demographic and clinical status, 2 ml of oxalated blood and 2 ml of clotted blood were taken. Eosinophil cells percentage and total IgE antibody levels were measured by counter and ELISA respectively. Data were analyzed by descriptive statistical, Fisher's exact and t- tests. Results: This study indicated that the total IgE levels 34 % of patients with asthma and 20% of control group were higher than normal, this difference was statistically significant (p<0.05). The 36% of cases showed Eosinophil above 4%, while the control group no positive cases were found, this difference was statistically significant (p<0.05). There was a significant correlation between the percentage of Eosinophil cells and extent of symptoms of asthma with its severity (p<0.05). A significant correlation was seen between total IgE levels and the percentage of Eosinophil in asthma patients (p<0.05). Conclusion: The amount of total IgE antibody and the percentage of eosinophil cells in patients with asthma are high. Due to these two factors associated with symptoms and severity it can be used of these two factors for controlling, prognosis and treatment of the disease. Key words: Asthma, IgE antibody, Eosinophi}, Keywords = {Key words: Asthma, IgE antibody, Eosinophi}, volume = {18}, Number = {10}, pages = {797-804}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-489-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-489-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2014} } @article{ author = {Mallaki, M and Shariati, M and Sepehrara, L}, title = {The Effect of Zonisamide on Sex Hormones Level and Testis Histological Changes in Adult MaleRat}, abstract ={Abstract Background and aim: Zonisamide is an inhibitor for glutamate neurotransmitter and gamma aminobutiric acid (GABA)-mediators. It also increases the total levels of serotonin. According to the importance of this drug in psychotherapy, its side effects on the endocrine system seem to be very important. This study was aimed to determine the effects of zonisamide on pituitary-gonad axis and spermatogenesis. Methods: In this experimental study, 50 adult male Wistar rats were divided in five groups of ten. The control group did not receive any medical treatment. The sham group received 1 ml distilled water as a solvent and three experimental groups were treated with 50, 100, 200 mg/ kg of zonisamide orally for 28 days.At the day of 29, blood samples and preparation of tissue section were taken from all groups. Serum concentrations of hormones were measured via Radio Immuno Assay (RIA). Using the SPSS software, the results were analyzed by using one-way analysis of variance (ANOVA) and Tukey tests. Results: The results showed that 100 and 200(mg/kg.b.w) of zonisamide could reduce the serum level of testosterone and dihydrotestosterone (DHT), while it increased the LH concentration. It should be noted that 200(mg/kg.b.w) of drug also enhanced the FSH level (P<0/001). Also, a considerable decline was observed in spermatogenesis chain at high doses of zonisamide. Conclusion: This study showed that high doses of zonisamide decrease the serum concentration of testosterone and dihydrotestosterone and the number of spermatogenic cells. It also increased the serum FSH and LH levels. Therefore, it is proposed that zonisamide may decrease the function of reproductive activity. Key words: Zonisamide, Reproduction, Rat}, Keywords = {Key words: Zonisamide, Reproduction, Rat}, volume = {18}, Number = {10}, pages = {805-815}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-490-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-490-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2014} } @article{ author = {Archin, T and Afzalian, E and Kargar, M and Ghasemi, Y}, title = {Molecular Identification of SHV,TEM, CTX-M β lactamases Genes and Antibiotics Resistance Pattern of k.pneumoniae Isolates Collected from ICU Patients of Namazi Hospital, Shiraz, Iran}, abstract ={Abstract Background and aim: β-lactamase enzymes producing bacteria ESBL have spread widely throughout the world. The production of enzymes induces bacterial resistance to a wide range of antibiotics which is leading to the limitation of infection control and correct treatment. The aim of the present study was to investigate patterns of antibiotic susceptibility to antibiotics and the presence of β-lactamase genes SHV, TEM, CTX-M, in Klebsiella pneumoniae isolates from clinical specimens of intensive care. Methods: Susceptibility of isolated bacteria against 10 antibiotics was determined by agar disk diffusion method according to the CLSI guidelines. The strains (DDST) were examined for the presence of the spectrum β-lactamase enzymes. Using E-test, the minimum inhibitory concentration (MIC) of the antibiotic was determined to cefotaxime. Moreover, SHV, TEM, CTX-M genes were identified by, Multiplex PCR method, and some of them were sequenced. Results: The antibiotic resistance against 10 antibiotics was determined. The highest percentage of isolates was resistant to ampicillin (100%) and sensitivity to imipenem was 1.66%). In this study, the majority of strains produced ESBL (60%). TEM gene in 34.38% and all three genes (TEM and SHV and CTX) at 33.13% of isolates were observed. Conclusion: The present study showed that the K. pneumoniae producing ESBL in patients in ICU are common. Therefore, the use of procedures and policies for infection control in hospitals and especially ICU is necessary. Key words: Klebsiella pneumoniae, ESBL, Multiplex PCR, antibiotic sensitivity}, Keywords = {Key words: Klebsiella pneumoniae, ESBL, Multiplex PCR, antibiotic sensitivity}, volume = {18}, Number = {10}, pages = {816-825}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-491-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-491-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2014} } @article{ author = {Saadat, S and Solhjoo, K and Kazemi, A and Mradaneh, J}, title = {Antibiotic Resistance Pattern of Staphylococcus aureus Strains Isolated from Personnel of Jahrom Hospitals in 2012}, abstract ={Abstract Background and aim: In recent decades, inappropriate antibiotic therapy has been led to the emergence of strains resistant to methicillin and vancomycin. Since the main source of infection and transmission of Staphylococcus aureus is by hospital staff, the aim of this study was to determine the antimicrobial susceptibility of S.aureus strains isolated from hospital staff of Jahrom. Undo edits Methods: In this cross - sectional study, 397 of the anterior nasal samples of medical personnel and hospital services were collected by swab. The identification of S.aureus was determined by biochemical tests and microbiology, and the antibiotic resistances of isolates were determined by disk diffusion method for 13 antibiotics. In this method, the inhibition zone for methicillin-resistant strains was ≤ 10 mm the minimum inhibitory concentrations (MIC) against antibiotic vancomycin, ticoplanin, linezolid and synercid were determined by E-test method. Results: In the present study, 11.3% of personals carried S. aureus in the nose. Among them, 90% were health care workers and 10% were health service workers. The most sensitivity was observed resistance to Ciprofloxacin, rifampin, linezolid and synercid (91.1%), but the lowest sensitivity was to penicillin (4.7%). of 9 MRSA strains, 1 strain was resistance to vancomycin and 2 strains were resistant to teicoplanin and linezolid. Conclusion: Because of S. aureus strains isolated from hospital staffs were resistant to most common antibiotics, identification and treatment of health care and health service workers can prevent nosocomial infections. Key words: Staphylococcu aureus carriers, hospital personnel, antibiotic resistance.}, Keywords = {Key words: Staphylococcu aureus carriers, hospital personnel, antibiotic resistance.}, volume = {18}, Number = {10}, pages = {826-835}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-492-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-492-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2014} } @article{ author = {SardariKashkooli, F and Sabeti, F and Mardani, HA and ShayestehFard, M}, title = {The Effect of Peer-Mentoring Program on Nursing Students’ Clinical Environment Stressors}, abstract ={Abstract Background & aim: Clinical training in nursing education is one of the most stressful experiences. Mentoring is a method that has been considered and different aspect of it such as effect on stress is argued. The present study is conducted to evaluate the effect of Peer-Mentoring program on Abadan College of nursing students in 2010-2011. Methods: In this Case-Control study, all second semester nursing students (n = 40) who were matched for age, gender, and GPA were divided in two case and control groups randomly (patients 19 and controls 21). Both groups spent their apprenticeship under the guidance of the instructor. In the case group, a 6th semester nursing student was assigned to 3-4 per second semester nursing student and, took the role of guiding and supporting them. The instruments for data collection were an individual characteristic form, and clinical experience assessment form. Pre- and post-tests were performed and the data analyzed using the SPSS 17 software. . Results: There was a significant difference between stress scores before and after of the intervention in both groups (p=0.00). Mean difference of clinical environment stress factors in two groups were not statistically significant (p=0.99). Conclusions: Peer-mentoring program is not significant effective on clinical environment stress reduction. Key Words: Nursing Education, Peer Mentoring, Clinical Environment Stressors}, Keywords = {Key Words: Nursing Education, Peer Mentoring, Clinical Environment Stressors}, volume = {18}, Number = {10}, pages = {836-846}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-493-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-493-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2014} } @article{ author = {Torabi, S and Mahmoudi, R and Rozbehi, A and JafariBarmak, M and Rad, P and Delaviz, H}, title = {Growth Factor and Laminin Effect with Muscular Fiber Sheath on Repairing of the Sciatica Nerve}, abstract ={Abstract Background & aim: Peripheral nerve injuries which can lead to a physical disability. If the defect is very low, direct suture without tension on both ends of the cut nerve regeneration is considered as a standard procedure. Otherwise, to reconstruct the axons, the gap must be filled by graft material in order to the guidance. Due to the similarity of the matrix tubular skeletal muscle and nerve muscles graft was used to repair in this study. Methods: In the present experimental study, 42 female Wistar rats were divided into three groups and underwent surgery. In the first group a narrow strip of muscle was prepared by freezing – thawing, and later sutured between the distal and proximal sciatic nerve. In the second group, the gap caused by muscle graft was regenerated and the nerve growth factor and laminin was injected into the graft. In the control group, the two ends of the cut nerve were hidden beneath the adjacent muscles. Next, a group of rats with sciatic functional index was investigated for the behavioral. On the other group were examined for histological studies after two months. Results: Sciatic functional index and Mean counts of myelinated fibers in two graft groups compared with the control group was significant) p<0.05). Statistical analysis was performed using ANOVA test. Conclusion: co-axially aligned muscle grafts were an appropriate alternative substitute for repairing. It seems that the nerve growth factor and laminin have a positive role in axonal regeneration and functional recovery acceleration. Key words: Sciatic Functional Index, muscle graft, NGF, Laminin}, Keywords = {Key words: Sciatic Functional Index, muscle graft, NGF, Laminin}, volume = {18}, Number = {10}, pages = {847-858}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-494-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-494-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2014} } @article{ author = {Rasoli, Y and Falahat, E}, title = {The Effect of Active Method of Problem Solving on Marital Conflicts in Yasuj, Iran}, abstract ={Abstract Background & aim: Marital conflicts are a lack of continuous and significant agreement between two spouses that provide unpleasant consequences for couples and families and create background for family breakdown. The Purpose of this study was to investigate the effects of marital conflict problem solving methods in Yasuj. Iran. Methods: In the present study, from all couples who had marital conflict referred to family counseling in Yasuj, Iran. 40 subjects (20 couples) were selected and randomly divided into two experimental and control groups. Measuring tools for marital conflict was questionnaire. A multivariate analysis of covariance (MANOVA) was used to analyze the significance of difference between the experimental and control groups. Results: The mean scores of marital conflict test group was (4/104), below the mean of control group (14/119). Whereas in other sub-scales (cooperation, sexuality, emotional response, protection of children, relationship with relatives, relationship with wife’s relatives and finance) the mean scores of experimental group was lower than controls (p <0.01). Conclusion: The method of the problem solving reduced the marital conflict of couples. In the method of solving problem with understanding and investigation of differences, the method of encounter and marital conflicts are considered. At the end, the most practical and efficient solution will be chosen and carried out. Keywords: Active Method, Problem Solving, Marital Conflict}, Keywords = {Keywords: Active Method, Problem Solving, Marital Conflict}, volume = {18}, Number = {10}, pages = {868-859}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-495-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-495-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2014} } @article{ author = {Hosseini, SE and Delerezh, N and AfzalAhangaran, N}, title = {The Effects of Royal Jelly on In-Vitro Cytotoxicity of K562 Cells and Peripheral Blood Mononuclear Cells}, abstract ={Abstract Background & aim: Royal jelly, secreted by worker bees, has different biological activities on cells and tissues. The aim of this study was to evaluate the effects of royal jelly on peripheral blood mononuclear cells and on the tumor category of K562 cell line. Methods: In the present experimental study, three subjects were selected separately with three repetitions. K562 (104 cells) and PBMC (105 cells) with different concentrations of royal jelly (5, 10, 25, 50 and 100 mg/ml) were cultured under standard conditions for 48 and 72 h separately. The fatality rate on PBMC cells and K562 cancer cells was evaluated by using MTT (Tetrazolium Dye-Reduction Assay). The number of viable cells in PBMC that were exposed for 48 hours with Royal Jelly was evaluated by trypan blue staining. Data were analyzed by ANOVA. Results: The royal jelly had no cytotoxicity effect on PBMC cells but at concentration of 50 and 100 mg/mL the cytotoxicity effect were observed on k562 cells whereas, at 10 and 25 mg/ml the number of PBMC viable cells increased. Conclusion: Due to the lack of lethality of royal jelly on PBMC cells and PBMC cell viability and an increase in the fatality rate of cancer cells in the future, royal jelly can be used as a potential candidate for treatment of leukemia. Keywords: Royal jelly, K562, peripheral blood mononuclear cell}, Keywords = {Keywords: Royal jelly, K562, peripheral blood mononuclear cell}, volume = {18}, Number = {11}, pages = {869-878}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-496-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-496-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2014} } @article{ author = {MarzbanAbbasAbadi, B and Tadjalli, M and DehghaniNazhvani, S}, title = {Effect of soy milk on thickness of cerebral cortex and hippocampus in newborn ovariectomized rats}, abstract ={Abstract Background & aim: Soy contains the largest concentration of isoflavones, they are structurally similar to estradiol and mimic its effects. The purpose of this study was to evaluate the effect of soy milk on thickness of cerebral cortex and hippocampus in newborn ovariectomized rats. Methods: The present experimental study was conducted on 30 newborn female rats. In day 7, 20 rats were randomly chosen and ovariectomy surgery was performed on them. Then the rats were divided to six groups of five rats each: control group, ovariectomized rats (no treatment), sham group and 3 groups of ovareictomaized rats treated by soy milk in doses 0.75, 1.5 and 3 ml/kg/day. In day 60, the brains of all rats were dissected and histological studies for determination of thickness of cerebral cortex and hippocampus were done. The collected data were analyzed with one-way ANOVA and Tukey tests. Results: Our results indicated that low estradiol following ovariectomy decreased thickness of cerebral cortex and hippocampal regions and soy milk in high dose increase the levels of estradiol, thickness of cerebral cortex and thickness of hippocampal regions. Conclusion: soy milk can compensate the effect of ovariectomy on thickness of cerebral cortex and hippocampal regions. Key words: Soy Milk, Hippocampus, Cerebral Cortex}, Keywords = {Key words: Soy Milk, Hippocampus, Cerebral Cortex }, volume = {18}, Number = {11}, pages = {879-887}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-497-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-497-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2014} } @article{ author = {Zarea, A and Asghari, GHR and Ghanadian, M and Yousefi, HA and YousofiDarani, H}, title = {Effect of Taxusbaccata leaves fractions on Trichomonasvaginalis growth in culture medium}, abstract ={Abstract Background & aim: Tichomoniasis is a common sexually transmitted disease (STD) caused by a protozoan parasite called Trichomonas vaginalis. Metronidazole, with vast side effects, is the main treatment for this infection. The aim of this study was to investigate the effect of the extract fractions of Taxusbaccata, on Trichomonas vaginalis in cultured medium. Methods: In the present study, asetonia dichloromethane extract of Taxusbaccata and hydroalcoholic fractions of 60% and 90% were collected and then dried. Their anti-trichomonas effect at doses of 200, 300, 400 and 500 μg/ml at 24, 48 and 72 hours on the TYIS33 culture media were studied. Data were analyzed using ANOVA test. .Results: The crude extract and fractions of 60% at different times at concentrations of 200, 300, 400 and 500 μg/ml showed higher anti-parasitic effects than 90% (p < 0.05). At concentration of 200 μg/ml of extract of 60% which causing 100% inhibition growth but the fraction of 90% showed 60% of inhibition growth. Conclusion: The effect of Taxusbaccata on Trichomonas may be a good alternative candidate for metronidazole. Key words: Taxusbaccata, Trichomonas vaginalis, Fracctions}, Keywords = {Key words: Taxusbaccata, Trichomonas vaginalis, Fracctions}, volume = {18}, Number = {11}, pages = {888-899}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-498-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-498-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2014} } @article{ author = {PanahiKokhdan, E and Mianabadi, M and Sadeghi, H and Khalaf, M}, title = {The Effects of Two Species of Daphne, Betulin and Betulinic Acid on Alkaline Phosphatase Activity in Two Human Cancer Cell lines, K562 and MCF-7}, abstract ={Abstract Background & aim: Changes of alkaline phosphatase activity is one of the symptoms of many diseases. The aim of this study was to evaluate the effect of two types of Daphne, Betulin and Betulinic acid, on alkaline phosphatase activity in K562 and MCF-7 cell lines, respectively. Methods: In this study, 106 cancer cell lines of K562 and MCF-7 were cultured in presence of 5% carbon dioxide at 37 ° C. at doses near the IC50. The viability of cells, inside and outside alkaline phosphatase activity and the amount of total protein in each treatment were studied. The collected data was analyzed with a multivariate analysis of variance (Nested Design) and Dunnett test. Results: The intracellular alkaline phosphatase activity of the cells showed different behavior compared to the extracellular alkaline phosphatase activity (p< 0.01). The highest increase of alkaline phosphatase activity in two cell lines (K562 and MCF-7) were 339% and 236% which was related to the treatment by macronata daphne. Conclusion: Unexpected increase in intracellular alkaline phosphatase activity in D. mucronata, D. oleides, Betulin, and Betulinic acid treatment may be due to changes in the composition of plasma membrane component and an increase the non-connected membrane of the protein which is due to the creation of more active proteins. Keywords: Daphne mucronata, Daphne oleoides, Alkaline Phosphatase, Betulinic Acid, Betulin}, Keywords = {Keywords: Daphne mucronata, Daphne oleoides, Alkaline Phosphatase, Betulinic Acid, Betulin}, volume = {18}, Number = {11}, pages = {900-909}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-499-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-499-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2014} } @article{ author = {BehnamMoghadam, M and Zeighami, R and Azimian, J and Jahanihashemi, H and Fotuhi, M}, title = {Side Effects of Intravenous Streptokinase in Different Age Groups Patients with Acute Myocardial Infarction}, abstract ={Abstract Background & aim: Myocardial infarction is one of the most common cardiovascular diseases. Streptokinase is used in patients with myocardial infarction with ST-segment elevation. The aim of this study was to compare the side effects of intravenous streptokinase in acute myocardial infarction patients in different age groups. Methods: In the present analytic descriptive study, the samples included 100 eligible patients which received intravenous streptokinase. The research instrument was a questionnaire consisting of two parts: the first part was used to measure the underlying data and the second part to evaluate the side effects of intravenous streptokinase,. Data were analyzed by chi-square statistical tests. Results: There were no significant adverse events between intravenous streptokinase and different age groups ((P>0.05).). The most common side effects of this drug were cardiovascular complications in different age groups. Conclusion: the use of streptokinase intravenous drug in different age groups is associated with risk of cardiovascular complications. Key words: age, side effects, streptokinase, acute myocardial infarction, thrombolytic therapy, ST elevation}, Keywords = {Key words: age, side effects, streptokinase, acute myocardial infarction, thrombolytic therapy, ST elevation}, volume = {18}, Number = {11}, pages = {910-917}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-500-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-500-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2014} } @article{ author = {Adibfard, E and Mirzaei, A and Pourelmi, T}, title = {Evaluation of Hepatoprotective Effects of Hydroalcoholic Extract of Green Pepper and Parsley on the Toxicity Induced by Carbon Tetrachloride in Rats}, abstract ={Abstract Background & aim: Green pepper and parsley have high antioxidant properties due to flavonoids and polyphenolic compounds. The aim of this study was to investigate the hepatoprotective effects of hydroalcoholic extract of green pepper and parsley on the toxicity induced by carbon tetrachloride in rats. Methods: In the present experimental study, 48 male Wistar rats were divided into six groups of eight. The first group (negative control) received olive oil, the second group receiving tetrachloride carbon and olive oil in equal proportions. The third and fourth groups (treatment groups) were treated with the tetrachloride carbon and olive oil equally and then exposed to extract of parsley and green pepper to the amount of 200 mg/kg separately. The fifth and six groups were treated with tetrachloride carbon and olive oil equally, and then separately exposed to 400 mg/kg of parsley and green pepper extract. The amount of total phenol and flavonoid samples and antioxidant activities were assessed by different methods. The collected data were analyzed by One-way ANOVA tests followed by Tukey test. Results: Intraperitoneal injection of 202, 191 and 183 In.U/L of carbon tetrachloride to positive control increased the activity of alkaline phosphatase, aspartate aminotransferase and alanine aminotransferase, respectively. The injection of carbon tetrachloride increased total bilirubin at the rate of4.8 mg/dl and also decreased protein and albumin at rate of 5.1 and 2.6 g/dl.Mqdartvtal respectively 1/5 and 6/2 g, was dL ( p <0.001). In the groups treated with the extract the activity of alkaline phosphatase, aspartate aminotransferase and alanine aminotransferase in the third to sixth groups were 121, 115 and 109, 130, 121 and 121, 112 109 and 98, 118, 114, and 119 respectively. The values of bilirubin, total protein and albumin, in the III group were: 3/8, 5/5 and 2/8, Group IV: 3/9, 5/3and 2/7, the V: 3/6, 5/8 and 3/1, the VI: 3/8, 5/6 and 3, respectively. Finaly, the amount of total bilirubin, total protein and albumin of groups’ three to sixth were obtained 3.8, 0, and 2.8, 3.9, 0.2 and 2.7, 3.6, 0.8 and 2.6, 3.8, 0.6, and3 respectively. Conclusions: Administration of green pepper and parsley extract at doses of 200 mg and 400 mg/kg could have a protective effect against liver damage induced by carbon tetrachloride. Keywords: green pepper and parsley, alkaline phosphatase, aspartate transaminase, alanine transaminase and protein.}, Keywords = {Keywords: green pepper and parsley, alkaline phosphatase, aspartate transaminase, alanine transaminase and protein. }, volume = {18}, Number = {11}, pages = {918-932}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-501-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-501-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2014} } @article{ author = {Shayanfar, M and Shirazi, M and Rashidkhani, B and Esmaillzadeh, A and HoushiarRad, A and Sharifi, G and Amirpour, M}, title = {The Association between Some Nutrients and Adult Gliomas: A Case-Control Study of Adult Gliomas}, abstract ={Abestract Background & aim: It has been estimated that about 30–40 percent of all cancers could be prevented by diet and lifestyle. In the present study, associations between food groups and some nutrients were studied in adult glioma. Methods: In the present hospital-based case-control study which took place in Tehran, Iran, from 2010 to 2012, socio-economic information, demographics, lifestyle factors, health and dietary intakes of 128 patients with glioma as cases, and 256 healthy controls, were collected through interviews and questionnaires. Logistic regression was used to estimate odds ratios. SPSS version 19 was used for all statistical analyses. Results: After adjusting for potential confounders, inverse associations between calcium intake and adult glioma and vitamin C were observed. (Highest tertile versus lowest: OR = 0.20, 95% CI = 0.87-0.46, P for trend = 0.001) and vitamin C (OR = 0.34, 95% CI = 0.15-0.76, P for trend = 0.002). In addition, we observed elevated ORs for highest vs. lowest tertile of cholesterol intake (OR = 2.78, 95% CI = 1.29-5.99, P for trend = 0.061). We observed no significant associations with adult glioma for intakes of total fat, carbohydrate, protein, vitamin A, vitamin E and beta carotene. Conclusion: the results showed that intake of calcium and vitamin C may possibly prevent glioma in adults. Key words: Gliomas, Adult, Ca, Vitamin C}, Keywords = {Key words: Gliomas, Adult, Ca, Vitamin C}, volume = {18}, Number = {11}, pages = {933-944}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-502-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-502-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2014} } @article{ author = {Jahedi, S and Refahi, Z and Sharifi, A and Rajaeechaleshtari, S}, title = {Predictive Power of Family Cohesion and Flexibility on Children’s’ Self - Esteem and Happiness in Female High School Students in Shiraz, Iran}, abstract ={Abstract ‌Background & aim: The role of family in shaping affective and cognitive characteristics of children, especially girls, who the future health of community depends on their mental health, is evident. The purpose of this study was to determine the predictive power of family cohesion and flexibility on self-esteem and happiness of children in high school girl students in Shiraz. Methods: In the present correlational study design, 303 cases of Shiraz secondary girl students who lived with their parents were chosen through the multistage random cluster sampling method. They responded to questionnaires for consistency of family, positives flexibility, Cooper Smith Self-esteem and Oxford Happiness scale. The data were analyzed by Pearson correlation and multiple regressions. Results Family consistency had significant positive power predictive for criterion variables self-esteem and happiness (p <0.05), whereas the flexibility had no such significance. Conclusion: Quality of operation of parents, communication and interaction in family life is one of the best determinants of behavior, health and well-being of children, including their self-esteem and happiness. Key words: Family cohesion, Family flexibility, Self-esteem, Happiness, Child}, Keywords = {Key words: Family cohesion, Family flexibility, Self-esteem, Happiness, Child}, volume = {18}, Number = {11}, pages = {945-954}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-503-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-503-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2014} }