TY - JOUR JF - yums-armaghan JO - armaghanj VL - 18 IS - 9 PY - 2013 Y1 - 2013/12/01 TI - The Effect of Essential Oil of Nigella sativa and Satureia hortensis on Promastigot Stage of Lishmania major TT - تأثیر اسانس‌های گیاهان مرزه و سیاه دانه بر روی فرم پروماستیگوت انگل لیشمانیا ماژور N2 - Abstract Background & aim: Leishmaniasis is a zoonotic disease caused by a protozoan parasite of the genus Leishmania. Traditionally, medicinal plants have been used for topical effects of leishmaniasis. The aim of this study was to evaluate the effect of the essential oil of Satureia hortensis and Nigella sativa on the Leishmania major. Methods: In this experimental study, the effects of the plant’s essential oils and savory black beans on the Leishmania major form were studied. Evaluation was determined based on the average of Leishmania parasites form survival after exposure to different concentrations of herbs and chemical drugs MA dose at different intervals. For this purpose, different extracts with ratios of 0.1, 0.2, 0.4, 0.8, 1.2, 1.6, and 2% were added. Different groups of this study were kept in the same condition (incubated at 26 ° C). The parasites were removed from the incubator and the numbers of viable parasites were counted after 24hours. Data were analyzed using descriptive statistics, Tukey test and GM. Results: There was a significant difference in reducing parasites on groups receiving Satureia hortensis and Nigella sativa with Glucantime (p SP - 687 EP - 698 AU - Pirali-Kheirabadi, KH AU - Dehghani-Samani, A AU - Adel, M AU - Hoseinpour, F AD - KW - Key words: Essential oil KW - Leishmaniasis KW - Nigella sativa KW - Satureia hortensis UR - http://armaghanj.yums.ac.ir/article-1-475-en.html ER -