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The Effect of Essential Oil of Nigella sativa and Satureia hortensis on Promastigot Stage of Lishmania major
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KH Pirali-Kheirabadi   1, A Dehghani-Samani , M Adel , F Hoseinpour |
| 1- , khpirali@yahoo.com |
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Abstract: (5497 Views) |
| Abstract
Background & aim: Leishmaniasis is a zoonotic disease caused by a protozoan parasite of the genus Leishmania. Traditionally, medicinal plants have been used for topical effects of leishmaniasis. The aim of this study was to evaluate the effect of the essential oil of Satureia hortensis and Nigella sativa on the Leishmania major.
Methods: In this experimental study, the effects of the plant’s essential oils and savory black beans on the Leishmania major form were studied. Evaluation was determined based on the average of Leishmania parasites form survival after exposure to different concentrations of herbs and chemical drugs MA dose at different intervals. For this purpose, different extracts with ratios of 0.1, 0.2, 0.4, 0.8, 1.2, 1.6, and 2% were added. Different groups of this study were kept in the same condition (incubated at 26 ° C). The parasites were removed from the incubator and the numbers of viable parasites were counted after 24hours. Data were analyzed using descriptive statistics, Tukey test and GM.
Results: There was a significant difference in reducing parasites on groups receiving Satureia hortensis and Nigella sativa with Glucantime (p <0.05).
Conclusion: Due to the increasing drug resistance of Leishmania, plant oils such as Satureia hortensis and Nigella sativa could be used as an alternative treatment for controlling leishmaniasis.
Key words: Essential oil, Leishmaniasis, Nigella sativa, Satureia hortensis |
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| Keywords: Key words: Essential oil, Leishmaniasis, Nigella sativa, Satureia hortensis |
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Full-Text [PDF 659 kb]
(1646 Downloads)
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Type of Study: Research |
Subject:
Special
Received: 2015/05/5 | Accepted: 2015/05/5 | Published: 2015/05/5
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