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:: Volume 25, Issue 3 (6-2020) ::
__Armaghane Danesh__ 2020, 25(3): 360-373 Back to browse issues page
Relationship of Mother's Hypertension, Age and Drug Use with Neonates Hyperbilirubinemia
N Mirazi 1, A Seif2 , F Zarei3 , N Pezeshki4 , Z Izadi5
1- Department of Biology, Bu-Ali Sina University, Hamedan, Iran , mirazi205@gmail.com
2- Department of Statistic, Bu-Ali Sina University, Hamedan, Iran
3- Department of Biology, Bu-Ali Sina University, Hamedan, Iran
4- Department of Neonatal Intensive Care Group, Fatemieh Hospital, Hamedan, Iran
5- Department of Horticulture, University of Nahavand, Nahavand,Iran
Abstract:   (2722 Views)
Background & aim: Neonatal hyperbilirubinemia is most common reason to re-admission in hospital. The mother's basic disorders are access and effects on this phenomenon. The aim of this study is to determinate and relation of  hypertension, age and drug addiction in mothers on neonatal hyperbilirubinemia.
 
Methods:  In this analytical descriptive study which done in 2018, the 300 mother's documents which refer to hospital for hospitalization their babies were studied. The questionnaire regarding maternal and their neonates were completed. Mothers and neonates information, degree of icterus, mother's hypertension and drug addiction history, family icterus history, kind of delivery, mother and neonate body weight, familiar wedding and number of labor were collected and evaluated. All data were evaluated statistically by SPSS and MINITAB method .
 
Results: The results of this study showed that the affection chance in neonates with mother's 21-30, 31-35 years old and 36 years old and up compare to neonates with their mothers under 20 years old (reference sheet) were about 2.95, 2.15 and 1.92 manifold respectively. The affection chance for hyperbilirubinemia in neonates with their mothers which have hypertension was 4 manifold compared to neonates with normal mothers. The affection chance for hyperbilirubinemia in neonates with their preterm mothers (less than 38 weeks) was 1.76 manifold mothers with complete term( more than 38 weeks). The affection chance for hyperbilirubinemia in neonates with their mothers which delivered naturally 1.56 manifold compared to mothers which labored her babies by cesarean section. There is to calculate probability of hyperbilirubinemia in neonates with using of predictive alternatives of mother's age in delivery time, pregnancy hypertension, pregnancy age and type of delivery with logistic regression presentation
 
Conclusion: This study explained that the mother's age in delivery time, pregnancy hypertension, age of gestation and type of labor have effects on neonatal hyperbilirubinemia. The fitting of logistic regression model on studying data and optimization operations  showed that the mother's age under 20 years, without hypertension, term gestation and cesarean delivery have reduce hyperbilirubinemia probability to 26% in neona 
Keywords: Neonatal Hyperbilirubinemia, Hypertension, Age, Logistic Regression
Full-Text [PDF 2023 kb]   (510 Downloads)    
Type of Study: Research | Subject: Physiology
Received: 2019/08/7 | Accepted: 2020/02/9 | Published: 2020/07/7
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Mirazi N, Seif A, Zarei F, Pezeshki N, Izadi Z. Relationship of Mother's Hypertension, Age and Drug Use with Neonates Hyperbilirubinemia. armaghanj 2020; 25 (3) :360-373
URL: http://armaghanj.yums.ac.ir/article-1-2591-en.html


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Volume 25, Issue 3 (6-2020) Back to browse issues page
ارمغان دانش Armaghane Danesh
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