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:: Volume 23, Issue 5 (11-2018) ::
__Armaghane Danesh__ 2018, 23(5): 536-546 Back to browse issues page
The Effect of Juglans Regia Green Pepper Extract on SeruThe Effect of Juglans Regia Green Pepper Extract on Serum Sugar, Lipid Profile and Liver Transaminases in Adult Male Rats With Streptozotocin-Diabeticm Sugar, Lipid Profile and
Z Erfanmanesh 1, SE Hosseini2 , S Khatamsaz2
1- Department of Biology, Islamic Azad University, Shiraz branch, Shiraz, Iran. , erfanmanesh_z@yahoo.com
2- Department of Biology, Islamic Azad University, Shiraz branch, Shiraz, Iran.
Abstract:   (491 Views)
Abstract
Background & aim: The anti-diabetic effects of Walnut green skin have attracted many researchers in the recent years.The aim of this study was to evaluate the effects of green skin extract on the serum level of sugar, lipid profile, and ALP, ALT, AST enzymes in adult male diabetic rats.
 
Methods: In the present experimental study, 32 adult male rats were divided into 4 groups of 8, including control, treated with medicine solvent, diabetic with 60 mg/kg dose of streptozotocin, and diabetic under 10 day treatment of 100 mg/kg dose of green skin extract of walnut groups. At the end, the serum level of glucose, triglyceride, high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), Alkaline Phosphatase (ALP), Alanine aminotransferase (ALT), and Aspartate aminotransferase (AST) enzymes are measured. Data were analyzed by ANOVA and Tukey tests.
 
Results:The results of this study indicated that in diabetic animals,  in comparison with control group, serum levels of ALP, ALT, AST enzymes, glucose, triglyceride, and LDL were increased, and HDL level decreased (P = 0.001). While in diabetic rats treated with green skin extract,in comparison with diabetic animals, the level of serum ALP, ALT, AST enzymes, glucose, triglyceride, and LDL decreased and HDL increased compared to diabetic animals(P = 0.001).
Conclusion:The green skin extract of walnut with anti-diabetic effects reduces glucose, liver transaminases, and lipid profiles in diabetic animals
 
 
Keywords: Green skin extract of walnut, diabet, Glucose, Lipid profile, ALP, ALT, AST, Rat
Full-Text [PDF 162 kb]   (148 Downloads)    
Type of Study: Research | Subject: Physiology
Received: 2018/05/24 | Accepted: 2018/11/3 | Published: 2018/11/3
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Erfanmanesh Z, Hosseini S, Khatamsaz S. The Effect of Juglans Regia Green Pepper Extract on SeruThe Effect of Juglans Regia Green Pepper Extract on Serum Sugar, Lipid Profile and Liver Transaminases in Adult Male Rats With Streptozotocin-Diabeticm Sugar, Lipid Profile and . Armaghane danesh. 2018; 23 (5) :536-546
URL: http://armaghanj.yums.ac.ir/article-1-2200-en.html


Volume 23, Issue 5 (11-2018) Back to browse issues page
ارمغان دانش Armaghane danesh
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