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:: Volume 22, Issue 6 (2-2018) ::
__Armaghane Danesh__ 2018, 22(6): 754-765 Back to browse issues page
Effect of Cardiac Rehabilitation with Severe Periodic Exercise Activity on Serum Glycine3 and Mutagenic Fraction in Patients with Heart Failure
M Siuf Jahromi1, KH Ebrahim2, MA Babaeibeigi3, H Nikbakht1
1- Department of Physical Education, Science and Research Branch, Islamic Azad University, Tehran, Iran,
2- Department of Physical Education, Shahid Beheshti University of Medical Sciences, Tehran, Iran, 3 , K-ebrahim@sbu.ac.ir
3- Cardiovascular Research Center, Shiraz University of Medical Sciences
Abstract:   (4399 Views)



Background and Aim: Cardiac rehabilitation improves the functional capacity of patients with heart failure. Therefore, the aim of this study was to investigate the effect of eight weeks of high frequency periodic training on mutagenic fraction and serigalctin 3 levels in cardiac patients.


Methods: In this quasi-experimental study, 24 heart patients (57.18 ± 6.17 years, 76.5 ± 13.89 kg, 25.34 ± 3.39 mm, 5.5 ± 5.5 cm) (169 cm) in Alzahra hospital in an injection fraction of 40-50% were randomly divided into two groups of severe routine exercises and control group. The exercise program included 12 repetitions of 1.5 minutes of activity on a bicycle and 8 repetitions of 1.5 times the activity on the treadmill, and between each period, 45 to 60 seconds of active rest with a 40-60% VO2peak intensity, which lasted for 8 Weekly and 3 sessions per week. The intensity of exercise with 50-60% of VO2peak started in the first week and was gradually increased by 10% every week and lasted from the week 4 to the end of the training protocol at an intensity of 80-90%. Blood samples were taken before and 48 hours after the last training session in the same conditions in both groups. Serigalcine 3 levels were measured using ELISA kit. The collected data were analyzed using independent t-test and paired T-test.


Results: The results showed that in the post-intensive training group, the level of Galactine 3 decreased (p = 0.003) and the mutation fraction increased (p = 0.001) in the training group, before the training, and in the control group Compared to pre and post test, Galactin Level 3 was found to increase (p = 0.001) and decrease in mutation fraction (p = 0.003). Comparing the two groups, the training group showed a significant decrease in Galactin 3 (p = 0.001) and a significant increase in the mutation fraction (p = 0.001).


Conclusion: Severe periodic exercises to reduce galactin levels 3 and increase the injectable fraction can improve cardiac function in cardiovascular patients.



Keywords: Severe Periodic Exercise, Heart Failure Patients, Galactin-3, Injection Fraction
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Type of Study: Research | Subject: Sport Physiology
Received: 2017/06/21 | Accepted: 2017/09/20 | Published: 2018/01/22
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Siuf Jahromi M, Ebrahim K, Babaeibeigi M, Nikbakht H. Effect of Cardiac Rehabilitation with Severe Periodic Exercise Activity on Serum Glycine3 and Mutagenic Fraction in Patients with Heart Failure. armaghanj 2018; 22 (6) :754-765
URL: http://armaghanj.yums.ac.ir/article-1-1915-en.html

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Volume 22, Issue 6 (2-2018) Back to browse issues page
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