:: Volume 22, Number 3 (6-2017) ::
__Armaghane Danesh__ 2017, 22(3): 390-404 Back to browse issues page
Eight-week aerobic training effects on Apelin-13 and insulin resistance in overweight men
Dr. Rahman Soori 1, Dr. Mohammad Reza Asad2, Mr. Mohammad Yari3, Dr. Mahsa Rastegar M.M.4
1- Associated professor University of Tehran , soorirahman@yahoo.com
2- Associated professor Payame Noor University
3- MSc Payame Noor University
4- PhD PhD of Exercise Physiology, Researcher of Iranian Research Center on Aging, the University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
Abstract:   (554 Views)

Background & aims: Obesity as a pandemic disease is the high accumulation of adipose tissue which secrets different hormones such as apelin. Apelin as an adipocytokine increases in obesity. Aerobic training induced apelin responses are not clarify well. So, we aimed to determine the effect of eight weeks aerobic training on Apelin-13 and insulin resistance in overweight men.

Methods: Current study was quasi-experiment design. Twenty-six overweight men with BMI between 27-30 kg/m2 were randomly enrolled in the present study following public call announcement and match to inclusion criteria. They accidently divided into submaximal-aerobic and control groups. The submaximal-aerobic group carried out exercise training for 24 continuous sessions (with 50-70% of maximum heart rate and 3 sessions/per-week) for eight weeks. The anthropometrical, VO2max and blood sampling assessments performed and later assessments were completed 24 hours after last training period. Then, whole of data were analyzed by Stata software at P<0.05 level. 

Results: Findings were elucidated that body weight and fat per cent significantly were decreased in exercise training group (p<0.05). Also, VO2max significantly were increased in exercise training group (p=0.0001). However, there were no significant changes in insulin resistance indices and Apelin-13 (p>0.05). In addition, there were direct and significant relationship between anthropometrical indices and HbA1c with Apelin-13 (p<0.05).

Conclusions: Obesity increases the possibility of metabolic diseases and insulin resistance. In the current study we represented that the internal factors of exercise, such as intensity, had meaningful effects on anthropometric features of overweight individuals but it was not enough for exercise induced-apelin-13 and insulin resistance changes.  According to this record, longer and higher intense exercise compare with the current study's protocol were recommended to beneficially decrease and control the incidence and catch the type II diabetes and cardiovascular diseases.

Keywords: Apelin-13, Aerobic exercise, Insulin resistance, Overweight
Full-Text [PDF 3656 kb]   (68 Downloads)    
Type of Study: Research | Subject: Sport Physiology
Received: 2016/10/17 | Accepted: 2017/07/8 | Published: 2017/07/25



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Volume 22, Number 3 (6-2017) Back to browse issues page