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:: Volume 21, Issue 5 (8-2016) ::
__Armaghane Danesh__ 2016, 21(5): 481-491 Back to browse issues page
Comparison of Endurance Training and Overtraining on the Balance of Th1 / Th2 in Male Wistar Rats
O Salehian1 , R Soori 2, AA Ravasi1 , S Choobine1
1- Department of Physical Education, Faculty of Sport Sciences, University of Tehran, Tehran, Iran
2- Department of Physical Education, Faculty of Sport Sciences, University of Tehran, Tehran, Iran , soorirahman@yahoo.com
Abstract:   (5059 Views)

Background & aim: The immune system is involved in numerous activities including inflammatory and anti-inflammatory activities. The activities associated with the production of Interferonγ and Interleukin-4. The present study investigated the effect of endurance training on the balance of these two cytokines pays more.

Methods: In the present study, 30 rats were selected and divided into 3 groups of 10: control, endurance and overtraining exercise. Endurance training protocol and overtraining were done for 12 weeks. Endurance training was done with the speed of 10 m/min in first week and 23m/min in last week. Overtraining protocol was done with the speed of 15 m/min in first week and 25 m/min in last week. Speleenectomy was done after interval training protocol, and then Interleukin 4 (IL4) and Interferon γ (IFNγ) were evaluated by the Eliza method. One-way ANOVA and Tukey post hoc test was used for data analysis.

Results: The results showed a significant increase in the amount of (IFNγ) and a decrease in the levels of IL4 in endurance training group (p=0.01). The results also exposed an increase in levels of IL4 and decrease IFNγ levels in overtraining group which was significant (p=0.01).

Conclusion: It can be concluded that the response to endurance training the amount of IFNγ and in response to overtraining the level of IL-4 was increased.

Keywords: endurance training, overtraining, IFNγ, IL4
Full-Text [PDF 174 kb]   (1641 Downloads)    
Type of Study: Research | Subject: Sport Physiology
Received: 2016/05/13 | Accepted: 2016/08/2 | Published: 2016/08/21
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Salehian O, Soori R, Ravasi A, Choobine S. Comparison of Endurance Training and Overtraining on the Balance of Th1 / Th2 in Male Wistar Rats. armaghanj 2016; 21 (5) :481-491
URL: http://armaghanj.yums.ac.ir/article-1-1347-en.html


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Volume 21, Issue 5 (8-2016) Back to browse issues page
ارمغان دانش Armaghane Danesh
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