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:: Volume 23, Issue 6 (1-2019) ::
__Armaghane Danesh__ 2019, 23(6): 666-682 Back to browse issues page
A Comparison Between the Effects of Eight Weeks of High Intensity Interval Training and Low Intensity Endurance Training on Expression of Hig2 and Intrahepatic Lipid Content in Rats with Non-Alcoholic Fatty Liver Diseases
M Bagheri1 , A Azamian Nazari 2, E Bani Talebi3 , MH Nasr Esfahani4
1- Department of Sports Physiology, Shahrekord University, Shahrekord, Iran,
2- Department of Sport Sciences, Shahrekord University, Shahrekord, Iran , azamianakbar@yahoo.com
3- Department of Sport Sciences, Shahrekord University, Shahrekord, Iran
4- Royan Biotechnology Research Center, Isfahan, Iran
Abstract:   (413 Views)

Abstract

Background & aim: Non-alcoholic liver disease is the main liver disease associated with malnourished diet and overweight habits. The purpose of this study was to compare the effects of 8 weeks of intense intolerant training (HIIT) and low intensity endurance training (LIET) on Hig2 gene expression and liver triglyceride content in fatty liver (NAFLD) rats.

 

Methods: In the present experimental study, 40 male wistar rats were randomly divided into four equal groups. The control group, LIET and HIIT, who consumed high fatty foods for the first sixteen weeks with the aim of developing fatty liver, and the sham group that used standard food during this period. The HIIT group's practice consisted of stages of extreme riding based on a percentage of maximum speed, which was separated by low-intensity running as active rest. The practice of the LIET group was also matched according to the distance traveled by the HIIT group. At the end of 8 weeks of training, the expression of Hig2 gene and liver fat content were measured. The collected data were analyzed using Kruskal-Wallis statistical tests.

 

Results: A significant difference was seen between the two groups in the expression of Hig2 (P = 0.026) and IHL (K2 = 32.84, p = 0.001). Significant differences were observed in Hig2 between the control group and the HIIT group (p = 0.031) and the control group with PID (p = 0.012), but no significant differences were observed in Hig2 between the HIIT group and the IR group (453/0 = p). Also, there were significant differences in IHL between control group and HIIT (p = 0.001) and control group with PID (p = 0.001). Also, there were significant differences in IHL between HIIT group and IR group (p = 0.003).

 

Conclusion: Severe periodic exercises and low-intensity continuous exercises by reducing the expression of Hig2 gene reduce the content of liver fat and improve NAFLD. Also, the reduction of liver fat in the severe periodic exercise group occurs independently of weight loss.

 

Keywords: Non-alcoholic fatty liver, Severe periodic exercise, Low endurance training, Protein derived from gene 2 induction of hypoxia, intrahepatic fatty
Full-Text [PDF 409 kb]   (95 Downloads)    
Type of Study: Research | Subject: Sport Physiology
Received: 2018/06/9 | Accepted: 2018/12/25 | Published: 2018/12/25
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Bagheri M, Azamian Nazari A, Bani Talebi E, Nasr Esfahani M. A Comparison Between the Effects of Eight Weeks of High Intensity Interval Training and Low Intensity Endurance Training on Expression of Hig2 and Intrahepatic Lipid Content in Rats with Non-Alcoholic Fatty Liver Diseases . Armaghane danesh. 2019; 23 (6) :666-682
URL: http://armaghanj.yums.ac.ir/article-1-2215-en.html


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